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学科主题药物依赖
Conditioned Place Preference Induced by Licit Drugs: Establishment, Extinction, and Reinstatement
Liu, Yu1; Le Foll, Bernard2; Liu, Yanli3; Wang, Xi1; Lu, Lin1
关键词conditioned place preference rewarding effect ethanol nicotine caffeine
刊名THESCIENTIFICWORLDJOURNAL
2008
DOI10.1100/tsw.2008.154
8页:1228-1245
收录类别SCI ; SSCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Environmental Sciences ; Multidisciplinary Sciences
研究领域[WOS]Environmental Sciences & Ecology ; Science & Technology - Other Topics
关键词[WOS]VENTRAL TEGMENTAL AREA ; DOPAMINE D-3 RECEPTOR ; CALCIUM-CHANNEL ANTAGONISTS ; ETHANOL-RELATED BEHAVIORS ; RAT NUCLEUS-ACCUMBENS ; FREELY MOVING RATS ; KNOCK-OUT MICE ; NICOTINIC RECEPTORS ; LOCOMOTOR-ACTIVITY ; MOTIVATIONAL PROPERTIES
英文摘要

The conditioned place preference (CPP) model has been widely used to evaluate the rewarding effects of abused drugs, and recently, the extinction and reinstatement phases of this paradigm have been used to assess relapse to drug seeking. The vast majority of studies have focused on CPP induced by illicit drugs, such as psychostimulants and opioids. Although legal psychoactive drugs, such as ethanol, nicotine, and caffeine, are more widely used than illegal drugs, the establishment, extinction, and reinstatement of CPP produced by these licit drugs are less well understood. The present review discusses the extant research on CPP induced by legal drugs. We first describe the CPP model and discuss the behavioral procedures used to induce CPP for ethanol, nicotine, and caffeine. We then summarize the neuronal substrates that underlie CPP induced by these drugs from a genetic perspective. Finally, we draw on findings from pharmacological studies and discuss the neurotransmitters and neurohormones underlying CPP produced by ethanol, nicotine, and caffeine.

语种英语
WOS记录号WOS:000261698000005
引用统计
被引频次:25[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62565
专题中国药物依赖性研究所
作者单位1.Soochow Univ, Coll Pharm, Suzhou, Peoples R China
2.Peking Univ, Natl Inst Drug Dependence, Beijing 100871, Peoples R China
3.Univ Toronto, Toronto, ON M5S 1A1, Canada
推荐引用方式
GB/T 7714
Liu, Yu,Le Foll, Bernard,Liu, Yanli,et al. Conditioned Place Preference Induced by Licit Drugs: Establishment, Extinction, and Reinstatement[J]. THESCIENTIFICWORLDJOURNAL,2008,8:1228-1245.
APA Liu, Yu,Le Foll, Bernard,Liu, Yanli,Wang, Xi,&Lu, Lin.(2008).Conditioned Place Preference Induced by Licit Drugs: Establishment, Extinction, and Reinstatement.THESCIENTIFICWORLDJOURNAL,8,1228-1245.
MLA Liu, Yu,et al."Conditioned Place Preference Induced by Licit Drugs: Establishment, Extinction, and Reinstatement".THESCIENTIFICWORLDJOURNAL 8(2008):1228-1245.
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