IR@PKUHSC  > 北京大学第二临床医学院
学科主题临床医学
One-stage human acellular nerve allograft reconstruction for digital nerve defects
Li, Xue-yuan1; Hu, Hao-liang1; Fei, Jian-rong1; Wang, Xin1; Wang, Tian-bing2; Zhang, Pei-xun2; Chen, Hong1
关键词nerve regeneration peripheral nerve allograft digital nerve nerve conduit nerve reconstruction nerve defect sensory nerve neural regeneration
刊名NEURAL REGENERATION RESEARCH
2015
DOI10.4103/1673-5374.150712
10期:1页:95-98
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Cell Biology ; Neurosciences
研究领域[WOS]Cell Biology ; Neurosciences & Neurology
关键词[WOS]CONDUITS ; REPAIR ; TRANSPLANTATION ; REGENERATION ; GRAFT
英文摘要

Human acellular nerve allografts have a wide range of donor origin and can effectively avoid nerve injury in the donor area. Very little is known about one-stage reconstruction of digital nerve defects. The present study observed the feasibility and effectiveness of human acellular nerve allograft in the reconstruction of < 5-cm digital nerve defects within 6 hours after injury. A total of 15 cases of nerve injury, combined with nerve defects in 18 digits from the Department of Emergency were enrolled in this study. After debridement, digital nerves were reconstructed using human acellular nerve allografts. The patients were followed up for 6-24 months after reconstruction. Mackinnon-Dellon static two-point discrimination results showed excellent and good rates of 89%. Semmes-Weinstein monofilament test demonstrated that light touch was normal, with an obvious improvement rate of 78%. These findings confirmed that human acellular nerve allograft for one-stage reconstruction of digital nerve defect after hand injury is feasible, which provides a novel trend for peripheral nerve reconstruction.

语种英语
WOS记录号WOS:000350098100024
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62571
专题北京大学第二临床医学院
北京大学第二临床医学院_创伤骨科
作者单位1.Ningbo 6 Hosp, Dept Hand Surg, Ningbo, Zhejiang, Peoples R China
2.Peking Univ, Peoples Hosp, Dept Trauma & Orthoped, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Li, Xue-yuan,Hu, Hao-liang,Fei, Jian-rong,et al. One-stage human acellular nerve allograft reconstruction for digital nerve defects[J]. NEURAL REGENERATION RESEARCH,2015,10(1):95-98.
APA Li, Xue-yuan.,Hu, Hao-liang.,Fei, Jian-rong.,Wang, Xin.,Wang, Tian-bing.,...&Chen, Hong.(2015).One-stage human acellular nerve allograft reconstruction for digital nerve defects.NEURAL REGENERATION RESEARCH,10(1),95-98.
MLA Li, Xue-yuan,et al."One-stage human acellular nerve allograft reconstruction for digital nerve defects".NEURAL REGENERATION RESEARCH 10.1(2015):95-98.
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