北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学临床肿瘤学院  > 超声科  > 期刊论文
学科主题: 临床医学
题名:
DIFFERENTIAL DIAGNOSIS OF GALLBLADDER WALL THICKENING: THE USEFULNESS OF CONTRAST-ENHANCED ULTRASOUND
作者: Xu, Jun-Mei1; Guo, Le-Hang1; Xu, Hui-Xiong1,2; Zheng, Shu-Guang1,2; Liu, Lin-Na1,2; Sun, Li-Ping1; Lu, Ming-De2; Xie, Xiao-Yan2; Wang, Wen-Ping3; Hu, Bing4; Yan, Kun5; Ding, Hong3; Tang, Shao-Shan6; Qian, Lin-Xue7; Luo, Bao-Ming8
关键词: Gallbladder ; Wall thickening ; Contrast-enhanced ultrasound ; Differential diagnosis ; Chronic cholecystitis ; Gallbladder carcinoma
刊名: ULTRASOUND IN MEDICINE AND BIOLOGY
发表日期: 2014-12-01
DOI: 10.1016/j.ultrasmedbio.2014.06.015
卷: 40, 期:12, 页:2794-2804
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: XANTHOGRANULOMATOUS CHOLECYSTITIS ; ULTRASONOGRAPHY ; DISEASE ; CANCER ; BENIGN ; CARCINOMA ; US ; ADENOMYOMATOSIS ; SONOGRAPHY ; FEATURES
英文摘要:

The purpose of this study was to evaluate the usefulness of contrast-enhanced ultrasound (CEUS) in the differential diagnosis of gallbladder wall (GBW) thickening and determine the predictors of malignant GBW thickening. One hundred fifty-nine patients with GBW thickening, including 76 men and 83 women, from eight institutions were enrolled. CEUS was performed after injection of a sulfur hexafluoride microbubble-based ultrasound contrast agent. Multiple logistic regression analysis was used to reveal independent predictors associated with malignant GBW thickening. The final diagnoses were 48 gallbladder carcinomas and 111 benign gallbladder diseases. Maximal thicknesses of the GBW in malignant and benign GBW thickening were 17.3 +/- 5.2 (6-30) mm and 8.6 +/- 5.1 (4-26) mm respectively (p < 0.001). CEUS revealed significant differences in intralesional vessels, enhancement homogeneity, time to hypo-enhancement, inner layer discontinuity, outer layer discontinuity and adjacent liver involvement (all p-values < 0.05) between malignant and benign GBW thickening. Patient age > 46.5 y, focal GBW thickening, inner layer discontinuity and outer layer discontinuity were found to be associated with malignancy by multiple logistic regression analysis (all p-values < 0.05). Receiver operating characteristic curve analysis revealed Az values for patient age, focal GBW thickening, inner wall discontinuity and outer wall discontinuity of 0.709 (95% confidence interval [CI]: 0.627-0.790), 0.714 (95% CI: 0.630-0.798), 0.860 (95% CI: 0.791-0.928) and 0.858 (95% CI: 0.783-0.933), respectively. CEUS is useful in the differential diagnosis between malignant and benign GBW thickening. Focal GBW thickening, inner wall discontinuity and outer wall discontinuity observed on CEUS are diagnostic clues for malignant GBW thickening. (C) 2014 World Federation for Ultrasound in Medicine & Biology.

语种: 英语
所属项目编号: 20114003 ; 2013SY066 ; 81301299 ; 2012045
项目资助者: Shanghai Health and Family Planning Commission ; National Natural Scientific Foundation of China ; Shanghai Talent Development Project from the Shanghai Human Resource and Social Security Bureau
WOS记录号: WOS:000345623400006
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62617
Appears in Collections:北京大学临床肿瘤学院_超声科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Tongji Univ, Shanghai Peoples Hosp 10, Dept Med Ultrasound, Shanghai 200072, Peoples R China
2.Sun Yat Sen Univ, Affiliated Hosp 1, Dept Med Ultrason, Guangzhou 510275, Guangdong, Peoples R China
3.Fudan Univ, Zhongshan Hosp, Dept Ultrasound, Shanghai 200433, Peoples R China
4.Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Dept Ultrasound Med, Shanghai 200030, Peoples R China
5.Peking Univ, Sch Oncol, Beijing Canc Inst, Dept Ultrasound, Beijing 100871, Peoples R China
6.China Med Univ, Shengjing Hosp, Dept Ultrasound, Shenyang, Peoples R China
7.Capital Med Univ, Beijing Friendship Hosp, Dept Ultrasound, Beijing, Peoples R China
8.Sun Yat Sen Univ, Affiliated Hosp 2, Dept Ultrasound, Guangzhou 510275, Guangdong, Peoples R China

Recommended Citation:
Xu, Jun-Mei,Guo, Le-Hang,Xu, Hui-Xiong,et al. DIFFERENTIAL DIAGNOSIS OF GALLBLADDER WALL THICKENING: THE USEFULNESS OF CONTRAST-ENHANCED ULTRASOUND[J]. ULTRASOUND IN MEDICINE AND BIOLOGY,2014,40(12):2794-2804.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Xu, Jun-Mei]'s Articles
[Guo, Le-Hang]'s Articles
[Xu, Hui-Xiong]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Xu, Jun-Mei]‘s Articles
[Guo, Le-Hang]‘s Articles
[Xu, Hui-Xiong]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace