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学科主题: 临床医学
题名:
Oddi sphincter preserved cholangioplasty with hepatico-subcutaneous stoma for hepatolithiasis
作者: Lian, Yu-Gui; Zhang, Wei-Tao; Xu, Zhi; Ling, Xiao-Feng; Wang, Li-Xin; Hou, Chun-Sheng; Wang, Gang; Cui, Long; Zhou, Xiao-Si
关键词: Hepatolithiasis ; stone recurrence ; Sphincter of Oddi ; hepaticoplasty ; hepatectomy
刊名: WORLD JOURNAL OF GASTROENTEROLOGY
发表日期: 2015-12-07
DOI: 10.3748/wjg.v21.i45.12865
卷: 21, 期:45, 页:12865-12872
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology
研究领域[WOS]: Gastroenterology & Hepatology
关键词[WOS]: INTRAHEPATIC STONES ; LIVER RESECTION ; LAPAROSCOPIC APPROACH ; WESTERN EXPERIENCE ; HEPATECTOMY ; OUTCOMES ; MANAGEMENT ; COHORT ; ERA
英文摘要:

AIM: To evaluate the long-term outcomes of Oddi sphincter preserved cholangioplasty with hepatico-subcutaneous stoma (OSPCHS) and risk factors for recurrence in hepatolithiasis.

METHODS: From March 1993 to December 2012, 202 consecutive patients with hepatolithiasis underwent OSPCHS at our department. The Oddi sphincter preserved procedure consisted of common hepatic duct exploration, stone extraction, hilar bile duct plasty, establishment of subcutaneous stoma to the bile duct. Patients with recurrent stones can undergo stone extraction and/or biliary drainage via the subcutaneous stoma which can be incised under local anesthesia. The long-term results were reviewed. Cox regression model was employed to analyze the risk factors for stone recurrence.

RESULTS: Ninety-seven (48.0%) OSPCHS patients underwent hepatic resection concomitantly. The rate of surgical complications was 10.4%. There was no perioperative death. The immediate stone clearance rate was 72.8%. Postoperative cholangioscopic lithotomy raised the clearance rate to 97.0%. With a median follow-up period of 78.5 mo (range: 2-233 mo), 24.8% of patients had recurrent stones, 2.5% had late development of cholangiocarcinoma, and the mortality rate was 5.4%. Removal of recurrent stones and/or drainage of inflammatory bile via subcutaneous stoma were conducted in 44 (21.8%) patients. The clearance rate of recurrent stones was 84.0% after subsequent choledochoscopic lithotripsy via subcutaneous stoma. Cox regression analysis showed that residual stone was an independent prognostic factor for stone recurrence.

CONCLUSION: In selected patients with hepatolithiasis, OSPCHS achieves excellent long-term outcomes, and residual stone is an independent prognostic factor for stone recurrence.

语种: 英语
WOS记录号: WOS:000365966600014
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62622
Appears in Collections:北京大学第三临床医学院_普通外科_期刊论文

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作者单位: Peking Univ, Hosp 3, Dept Gen Surg, Beijing 100191, Peoples R China

Recommended Citation:
Lian, Yu-Gui,Zhang, Wei-Tao,Xu, Zhi,et al. Oddi sphincter preserved cholangioplasty with hepatico-subcutaneous stoma for hepatolithiasis[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2015,21(45):12865-12872.
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