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学科主题: 临床医学
题名:
Tc-99m-N, N ′-bis(aminoethyl)propanediamine hexaacetic acid (BPHA): a glomerular filtration agent similar to Tc-99m-DTPA
作者: Liu, GZ; Zhang, CL; Liu, F; Wang, RF; Fu, ZL; Li, GQ; Miao, ZX
关键词: kidney ; glomerular filtration ; technetium-99m ; imaging
刊名: NUCLEAR MEDICINE AND BIOLOGY
发表日期: 2002-05-01
卷: 29, 期:4, 页:399-404
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: CONCISE COMMUNICATION ; QUALITY-CONTROL ; DTPA
英文摘要:

Investigations on the biodistribution of Tc-99m-BPHA in normal and probenecid treated mice and a comparison with Tc-99m-DTPA injected mice suggested that Tc-99m-BPHA is also a glomerular filtration agent. Whole body radioactivity measurements in mice and rabbits after administration of Tc-99m-BPHA showed negligible whole body radioactivity at 24 h. Excellent kidney images both in rabbits and a human volunteer were obtained. The significance of higher GFR estimates using Tc-99m-BPHA compared to Tc-99m-DTPA is discussed. (C) 2002 Elsevier Science Inc. All rights reserved.

语种: 英语
WOS记录号: WOS:000175794400003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62673
Appears in Collections:北京大学第一临床医学院_核医学科_期刊论文

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作者单位: 1.China Inst Atom Energy, Dept Isotope, Beijing 102413, Peoples R China
2.Beijing Med Univ, Sch Clin Med 1, Dept Nucl Med, Xishiku 100034, Peoples R China

Recommended Citation:
Liu, GZ,Zhang, CL,Liu, F,et al. Tc-99m-N, N ′-bis(aminoethyl)propanediamine hexaacetic acid (BPHA): a glomerular filtration agent similar to Tc-99m-DTPA[J]. NUCLEAR MEDICINE AND BIOLOGY,2002,29(4):399-404.
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