|Effect of anterior chamber paracentesis on initial treatment of acute angle closure|
|Yang, Xuejiao1; Su, Wenru1; Wang, Mei2; Bai, Yujing3; Li, Yiqing1; Ge, Jian1; Zhuo, Yehong1|
|刊名||CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE|
|WOS标题词||Science & Technology|
|关键词[WOS]||LASER PERIPHERAL IRIDOPLASTY ; OPTICAL COHERENCE TOMOGRAPHY ; NERVE-FIBER LAYER ; DECOMPRESSION RETINOPATHY ; INTRAOCULAR-PRESSURE ; LONGITUDINAL CHANGES ; ASIAN POPULATION ; ACUTE ELEVATION ; UVEAL EFFUSION ; VISUAL-FIELD|
Objective: To compare anterior chamber paracentesis (ACP) with standard medical management of acute primary angle closure (APAC).
Design: Prospective study.
Participants: Patients with APAC and intraocular pressure (IOP) >= 50 mm Hg were enrolled.
Methods: Patients were randomized to receive ACP and medical treatment (group 1) or medical management alone (group 2).
Results: There were 26 patients (mean age 69.3 +/- 10.4 years, 31 eyes) in group 1 and 28 patients (mean age 67.0 +/- 9.7 years, 30 eyes) in group 2. The IOP in group 1 was significantly lower at 15 minutes, 30 minutes, and 1 hour after treatment (p < 0.05). At 1, 2, and 24 hours after treatment, visual acuity was significantly better in group 1 than in group 2. At each time point after treatment, the grade of corneal edema was not different between the groups. Pain score at 1 and 2 hours after treatment was significantly lower in group 1 than in group 2; however, no difference was noted at 24 hours after treatment. The mean follow-up period in group 1 was 16.1 +/- 1.3 months and in group 2 was 15.6 +/- 1.4 months (p = 0.803). At last follow-up, IOP, pupil size, number of eyes with nonreactive pupils, and centre endothelial cell counts were not different; however, visual acuity was significantly better in group 1 (0.43 +/- 0.06 logMAR vs 0.74 +/- 0.10 logMAR, p = 0.007).
Conclusions: Immediate ACP is a safe and effective for rapidly lowering IOP, and is associated with better visual acuity than medical treatment alone.
|资助机构||Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme|
|作者单位||1.Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, Guangzhou 510060, Guangdong, Peoples R China|
2.Sun Yat Sen Univ, Dept Ophthalmol, Sun Yat Sen Med Hosp, Guangzhou 510060, Guangdong, Peoples R China
3.Peking Univ, Peoples Hosp, Minist Educ, Key Lab Vis Loss & Restorat,Dept Ophthalmol, Beijing 100871, Peoples R China
|Yang, Xuejiao,Su, Wenru,Wang, Mei,et al. Effect of anterior chamber paracentesis on initial treatment of acute angle closure[J]. CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE,2013,48(6):553-558.|
|APA||Yang, Xuejiao.,Su, Wenru.,Wang, Mei.,Bai, Yujing.,Li, Yiqing.,...&Zhuo, Yehong.(2013).Effect of anterior chamber paracentesis on initial treatment of acute angle closure.CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE,48(6),553-558.|
|MLA||Yang, Xuejiao,et al."Effect of anterior chamber paracentesis on initial treatment of acute angle closure".CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE 48.6(2013):553-558.|