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学科主题: 临床医学
题名:
Effect of anterior chamber paracentesis on initial treatment of acute angle closure
作者: Yang, Xuejiao1; Su, Wenru1; Wang, Mei2; Bai, Yujing3; Li, Yiqing1; Ge, Jian1; Zhuo, Yehong1
刊名: CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE
发表日期: 2013-12-01
DOI: 10.1016/j.jcjo.2013.04.012
卷: 48, 期:6, 页:553-558
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Ophthalmology
研究领域[WOS]: Ophthalmology
关键词[WOS]: LASER PERIPHERAL IRIDOPLASTY ; OPTICAL COHERENCE TOMOGRAPHY ; NERVE-FIBER LAYER ; DECOMPRESSION RETINOPATHY ; INTRAOCULAR-PRESSURE ; LONGITUDINAL CHANGES ; ASIAN POPULATION ; ACUTE ELEVATION ; UVEAL EFFUSION ; VISUAL-FIELD
英文摘要:

Objective: To compare anterior chamber paracentesis (ACP) with standard medical management of acute primary angle closure (APAC).

Design: Prospective study.

Participants: Patients with APAC and intraocular pressure (IOP) >= 50 mm Hg were enrolled.

Methods: Patients were randomized to receive ACP and medical treatment (group 1) or medical management alone (group 2).

Results: There were 26 patients (mean age 69.3 +/- 10.4 years, 31 eyes) in group 1 and 28 patients (mean age 67.0 +/- 9.7 years, 30 eyes) in group 2. The IOP in group 1 was significantly lower at 15 minutes, 30 minutes, and 1 hour after treatment (p < 0.05). At 1, 2, and 24 hours after treatment, visual acuity was significantly better in group 1 than in group 2. At each time point after treatment, the grade of corneal edema was not different between the groups. Pain score at 1 and 2 hours after treatment was significantly lower in group 1 than in group 2; however, no difference was noted at 24 hours after treatment. The mean follow-up period in group 1 was 16.1 +/- 1.3 months and in group 2 was 15.6 +/- 1.4 months (p = 0.803). At last follow-up, IOP, pupil size, number of eyes with nonreactive pupils, and centre endothelial cell counts were not different; however, visual acuity was significantly better in group 1 (0.43 +/- 0.06 logMAR vs 0.74 +/- 0.10 logMAR, p = 0.007).

Conclusions: Immediate ACP is a safe and effective for rapidly lowering IOP, and is associated with better visual acuity than medical treatment alone.

语种: 英语
项目资助者: Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme
WOS记录号: WOS:000331149800036
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62696
Appears in Collections:北京大学第二临床医学院_期刊论文

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作者单位: 1.Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, Guangzhou 510060, Guangdong, Peoples R China
2.Sun Yat Sen Univ, Dept Ophthalmol, Sun Yat Sen Med Hosp, Guangzhou 510060, Guangdong, Peoples R China
3.Peking Univ, Peoples Hosp, Minist Educ, Key Lab Vis Loss & Restorat,Dept Ophthalmol, Beijing 100871, Peoples R China

Recommended Citation:
Yang, Xuejiao,Su, Wenru,Wang, Mei,et al. Effect of anterior chamber paracentesis on initial treatment of acute angle closure[J]. CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE,2013,48(6):553-558.
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