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Time Course of Depression and One-Year Prognosis of Patients with Stroke in Mainland China
Zhang, Ning1; Wang, Chun-Xue1; Wang, An-Xin1; Bai, Ying1; Zhou, Yong1; Wang, Yi-Long1; Zhang, Tong1; Zhou, Juan2; Yu, Xin3; Sun, Xin-Yu3; Liu, Zhao-Rui3; Zhao, Xing-Quan1; Wang, Yong-Jun1; Prospective Cohort Study Incidence
关键词Cohort studies Depression Incidence Prognosis Prospective studies Risk factors Stroke
刊名CNS NEUROSCIENCE & THERAPEUTICS
2012
DOI10.1111/j.1755-5949.2012.00312.x
18期:6页:475-481
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Neurosciences ; Pharmacology & Pharmacy
资助者Beijing Science and Technology Committee ; National Science Foundation ; Beijing Health Bureau ; National 11th Five-year Scientific and Technological Brainstorm Project ; Pfizer Pharmaceutical Company ; Beijing Science and Technology Committee ; National Science Foundation ; Beijing Health Bureau ; National 11th Five-year Scientific and Technological Brainstorm Project ; Pfizer Pharmaceutical Company
研究领域[WOS]Neurosciences & Neurology ; Pharmacology & Pharmacy
关键词[WOS]MODIFIED RANKIN SCALE ; QUALITY-OF-LIFE ; POSTSTROKE DEPRESSION ; ISCHEMIC-STROKE ; BARTHEL INDEX ; SYMPTOMS ; INTERVENTION ; DETERMINANTS ; ASSOCIATION ; PREVALENCE
英文摘要

Aims: To investigate the incidence of depression at different time points within the first year after stroke in mainland China and to identify risk factors related to a poor 1-year prognosis in stroke patients. Methods: Subjects with acute cerebrovascular diseases were recruited and enrolled from 56 hospitals in mainland China between April 2008 and April 2010. Demographic data, previous disease history, and clinical data were collected. Four follow-up visits were occurred within the first year after stroke. The modified Rankin Scale =2 represents an unfavorable prognosis. Depression was diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition and was divided into persistent, recurrent and transient types. Results: The 1-year cumulative incidence of depression in stroke patients was 41.8%. Logistic regression analysis showed that the 1-year prognosis level was associated with age, disability before onset, neurological functional deficit level at admission, and a range of depression types. The odds ratio for persistent depression is the highest (OR=7.615, P<0.0001, 95% confidence interval 5.01111.572). Conclusions: In our study, depression occurred in >40% of patients within the first year after stroke. Persistent depression is the first independent determinant of prognosis during the first year after stroke.

语种英语
所属项目编号7102050 ; 81071115 ; 2009-009 ; 2006BA101A11
资助者Beijing Science and Technology Committee ; National Science Foundation ; Beijing Health Bureau ; National 11th Five-year Scientific and Technological Brainstorm Project ; Pfizer Pharmaceutical Company ; Beijing Science and Technology Committee ; National Science Foundation ; Beijing Health Bureau ; National 11th Five-year Scientific and Technological Brainstorm Project ; Pfizer Pharmaceutical Company
WOS记录号WOS:000304762600007
Citation statistics
Cited Times:13[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62709
Collection北京大学精神卫生研究所
作者单位1.Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing 100050, Peoples R China
2.Peking Univ, Inst Mental Hlth, Beijing, Peoples R China
3.Capital Med Univ, Beijing Daxin Dist Hosp, Dept Neurol, Beijing 100050, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Ning,Wang, Chun-Xue,Wang, An-Xin,et al. Time Course of Depression and One-Year Prognosis of Patients with Stroke in Mainland China[J]. CNS NEUROSCIENCE &amp; THERAPEUTICS,2012,18(6):475-481.
APA Zhang, Ning.,Wang, Chun-Xue.,Wang, An-Xin.,Bai, Ying.,Zhou, Yong.,...&Prospective Cohort Study Incidence.(2012).Time Course of Depression and One-Year Prognosis of Patients with Stroke in Mainland China.CNS NEUROSCIENCE & THERAPEUTICS,18(6),475-481.
MLA Zhang, Ning,et al."Time Course of Depression and One-Year Prognosis of Patients with Stroke in Mainland China".CNS NEUROSCIENCE & THERAPEUTICS 18.6(2012):475-481.
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