IR@PKUHSC  > 北京大学基础医学院  > 神经生物学系
学科主题基础医学
Simultaneous CBF and BOLD mapping of high frequency acupuncture induced brain activity
Zhang, Yue1; Glielmi, Christopher B.2; Jiang, Yin3; Wang, Jing1; Wang, Xiaoying4; Fang, Jing1; Cui, Cailian3; Han, Jisheng3; Hu, Xiaoping2; Zhang, Jue1
关键词High frequency electroacupuncture fMRI Cerebral blood flow Blood oxygenation level dependent Hegu
刊名NEUROSCIENCE LETTERS
2012-11-14
DOI10.1016/j.neulet.2012.09.050
530期:1页:12-17
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Neurosciences
研究领域[WOS]Neurosciences & Neurology
关键词[WOS]POSITRON-EMISSION-TOMOGRAPHY ; ELECTROACUPUNCTURE ANALGESIA ; ACUPOINT STIMULATION ; AFFECTIVE DIMENSION ; FUNCTIONAL MRI ; PAIN ; FMRI ; ACTIVATION ; MODULATION ; MECHANISMS
英文摘要

This study mapped brain activity elicited by high frequency electroacupuncture by simultaneously using blood oxygenation level dependent (BOLD) and cerebral blood flow (CBF) contrasts. Forty subjects participated in the study, in which twenty ones were imaged during electrical acupoint stimulation (EAS) to the left LI4 acupoint at a maximal intensity without pain, and the others were with a minimal-EAS at a just detectible intensity. Both BOLD and CBF data were acquired simultaneously during alternating blocks of rest and stimulation. The results showed that the minimal-EAS mostly induced the activities in somatosensory region, including those in inferior parietal lobule, SII, insula, and thalamus. On the other hand, EAS activated more including also posterior middle cingulate cortex (pMCC), and deactivated superior temporal gyrus. Moreover, deactivation was found in posterior cingulated cortex (PCC), precuneus from BOLD and in culmen of cerebellum, caudate from CBF. The comparison between EAS and minimal-EAS revealed deactivation in the default mode network in both BOLD and CBF signals, activation in thalamus, insula, and caudal anterior cingulate cortex (ACC) in the CBF signal alone, and deactivation in putamen, rostral ACC and parahippocampal gyrus in the BOLD signal alone. This study provides, for the first time, simultaneous CBF and BOLD responses to high frequency EAS at the LI4 acupoint, revealing concordant and complementary insights into the neural effects of EAS, including modulation of subcortical structures and limbic system. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

语种英语
WOS记录号WOS:000311664000003
资助机构Georgia Tech/Emory University/Peking University
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62728
专题北京大学基础医学院_神经生物学系
北京大学基础医学院
北京大学第一临床医学院_医学影像科
作者单位1.Peking Univ, Coll Engn, Beijing 100871, Peoples R China
2.Emory Univ, Dept Biomed Engn, Georgia Inst Technol, Atlanta, GA 30322 USA
3.Peking Univ, Neurosci Res Inst, Beijing 100871, Peoples R China
4.Peking Univ, Dept Radiol, Hosp 1, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Yue,Glielmi, Christopher B.,Jiang, Yin,et al. Simultaneous CBF and BOLD mapping of high frequency acupuncture induced brain activity[J]. NEUROSCIENCE LETTERS,2012,530(1):12-17.
APA Zhang, Yue.,Glielmi, Christopher B..,Jiang, Yin.,Wang, Jing.,Wang, Xiaoying.,...&Zhang, Jue.(2012).Simultaneous CBF and BOLD mapping of high frequency acupuncture induced brain activity.NEUROSCIENCE LETTERS,530(1),12-17.
MLA Zhang, Yue,et al."Simultaneous CBF and BOLD mapping of high frequency acupuncture induced brain activity".NEUROSCIENCE LETTERS 530.1(2012):12-17.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Simultaneous CBF and(549KB)期刊论文出版稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhang, Yue]的文章
[Glielmi, Christopher B.]的文章
[Jiang, Yin]的文章
百度学术
百度学术中相似的文章
[Zhang, Yue]的文章
[Glielmi, Christopher B.]的文章
[Jiang, Yin]的文章
必应学术
必应学术中相似的文章
[Zhang, Yue]的文章
[Glielmi, Christopher B.]的文章
[Jiang, Yin]的文章
相关权益政策
暂无数据
收藏/分享
文件名: Simultaneous CBF and BOLD mapping of high frequency acupuncture induced brain activity.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。