|Characteristics of the saliva flow rates of minor salivary glands in healthy people|
|Wang, Zhen1; Shen, Ming-Ming2; Liu, Xiao-Jing1; Si, Yan3; Yu, Guang-Yan1|
|关键词||Minor salivary gland Saliva Saliva secretion Saliva flow rate Salivary gland|
|刊名||ARCHIVES OF ORAL BIOLOGY|
|WOS标题词||Science & Technology|
|类目[WOS]||Dentistry, Oral Surgery & Medicine|
|研究领域[WOS]||Dentistry, Oral Surgery & Medicine|
|关键词[WOS]||HUMAN LABIAL GLANDS ; SECRETION RATES ; WHOLE SALIVA ; DRY MOUTH ; AGE ; VARIABILITY ; ADULTS ; VOLUME|
Objectives: To investigate the normal range and characteristics of saliva secretion in the minor salivary glands (MSGs).
Design: The flow rates of MSGs were measured in 4 anatomical locations of oral mucosa, and the relationship between MSG flow rates and whole saliva flow rates were assessed in 300 healthy subjects stratified by age and sex. An additional 30 young females were further evaluated for flow symmetry, effects of stimulation, circadian effects in MSGs, and the relationship with the flow rates of major salivary glands.
Results: (1) The mean saliva flow rates were 2.10 +/- 0.66 (lower labial glands), 2.14 +/- 0.62 (upper labial glands), 2.88 +/- 0.72 (buccal glands) and 2.15 +/- 0.51 (palatal glands) mu l/min/cm(2), respectively. The flow rate of buccal glands was significantly higher than the rates of SMGs in other locations (P < 0.01). (2) 5-year-old children had the lowest MSG flow rates (P < 0.0001) while the 10-14-year-old group had the highest (P < 0.001). (3) MSG flow rates were independent of sex (P > 0.05), right vs. left (P > 0.05), and citric acid (2.5%) stimulation (P > 0.05). (4) Only labial MSG displayed a significant secretory circadian rhythm with the highest rate in the evening (P < 0.05). (5) A weak correlation was found between the flow rate of palatal glands and that of unstimulated whole saliva (r = 0.195, P = 0.007).
Conclusions: Our findings provide a reference for functional evaluation of MSGs and for donor site selection of MSG transplantation for treatment of severe dry eye syndrome. (C) 2014 Elsevier Ltd. All rights reserved.
|作者单位||1.Peking Univ, Sch & Hosp Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100081, Peoples R China|
2.Hebei Med Univ, Hosp 2, Sch Stomatol, Dept Oral & Maxillofacial Surg, Shijiazhuang 050000, Peoples R China
3.Peking Univ, Sch & Hosp Stomatol, Dept Prevent Dent, Beijing 100081, Peoples R China
|Wang, Zhen,Shen, Ming-Ming,Liu, Xiao-Jing,et al. Characteristics of the saliva flow rates of minor salivary glands in healthy people[J]. ARCHIVES OF ORAL BIOLOGY,2015,60(3):385-392.|
|APA||Wang, Zhen,Shen, Ming-Ming,Liu, Xiao-Jing,Si, Yan,&Yu, Guang-Yan.(2015).Characteristics of the saliva flow rates of minor salivary glands in healthy people.ARCHIVES OF ORAL BIOLOGY,60(3),385-392.|
|MLA||Wang, Zhen,et al."Characteristics of the saliva flow rates of minor salivary glands in healthy people".ARCHIVES OF ORAL BIOLOGY 60.3(2015):385-392.|