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学科主题: 临床医学
题名:
Primary Diffuse-Type Tenosynovial Giant Cell Tumor of the Spine: A Report of 3 Cases and Systemic Review of the Literature
作者: Wang, Kai1; Zhu, Bin1; Yang, Shaomin2; Liu, Zhongjun1; Yu, Miao1; Liu, Xiaoguang1
关键词: Tenosynovial giant cell tumor ; Diffuse type ; Spinal neoplasms ; PVNS ; Systemic review
刊名: TURKISH NEUROSURGERY
发表日期: 2014-09-01
DOI: 10.5137/1019-5149.JTN.9594-13.1
卷: 24, 期:5, 页:804-813
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Surgery
研究领域[WOS]: Neurosciences & Neurology ; Surgery
关键词[WOS]: PIGMENTED VILLONODULAR SYNOVITIS ; LUMBAR FACET JOINT ; TENDON SHEATH ; VERTEBRAL COLUMN ; CERVICAL-SPINE ; THORACIC SPINE ; DIAGNOSIS
英文摘要:

Three patients with spinal primary diffuse-type tenosynovial giant cell tumor (DTGCT) received surgical treatment in our department between 2002 and 2012. All 3 patients were female and aged 23, 33, and 44 years. The mean time from symptom onset to diagnosis was 17 months (range, 5-24 months). One case involved the Cl right lateral mass and C2 vertebral body, the second involved the C1-2 left lateral masses and C2 vertebral body, and the third involved the C5-7 left lateral mass and C6 vertebral body. All patients underwent computed tomography-guided biopsy to confirm the diagnosis of tenosynovial giant cell tumor. Gross total resection was achieved in all patients, including 2 piecemeal resections and 1 en-bloc resection. The mean follow-up time was 6 years (range, 1-11 years), and there was no sign of recurrence in the patients. Seventy cases have been identified so far in the English literature. The male to female ratio is 1:1.38. The mean patient age is 38.5 +/- 17.9 years. The tumor distribution includes 32 cases in the cervical spine, 14 in the thoracic spine, 22 in the lumbar spine, and 1 in the sacrococcygeal region. The recurrence rate for patients who underwent gross total resection was 7.7%, and tumor progression was observed in 66.7% of patients who underwent subtotal resection. Above all, DTGCT is a rare primary spinal neoplasm. Preoperative image-guided biopsies play an important role in the diagnosis and treatment strategy. Gross total resection is the best treatment strategy and can reduce the recurrence rate.

语种: 英语
WOS记录号: WOS:000343531700034
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62749
Appears in Collections:北京大学第三临床医学院_骨科_期刊论文

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作者单位: 1.Peking Univ, Hosp 3, Dept Orthopaed, Beijing 100871, Peoples R China
2.Peking Univ, Hlth & Sci Ctr, Dept Pathol, Beijing 100871, Peoples R China

Recommended Citation:
Wang, Kai,Zhu, Bin,Yang, Shaomin,et al. Primary Diffuse-Type Tenosynovial Giant Cell Tumor of the Spine: A Report of 3 Cases and Systemic Review of the Literature[J]. TURKISH NEUROSURGERY,2014,24(5):804-813.
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