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Primary Diffuse-Type Tenosynovial Giant Cell Tumor of the Spine: A Report of 3 Cases and Systemic Review of the Literature
Wang, Kai1; Zhu, Bin1; Yang, Shaomin2; Liu, Zhongjun1; Yu, Miao1; Liu, Xiaoguang1
关键词Tenosynovial giant cell tumor Diffuse type Spinal neoplasms PVNS Systemic review
刊名TURKISH NEUROSURGERY
2014-09-01
DOI10.5137/1019-5149.JTN.9594-13.1
24期:5页:804-813
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Clinical Neurology ; Surgery
研究领域[WOS]Neurosciences & Neurology ; Surgery
关键词[WOS]PIGMENTED VILLONODULAR SYNOVITIS ; LUMBAR FACET JOINT ; TENDON SHEATH ; VERTEBRAL COLUMN ; CERVICAL-SPINE ; THORACIC SPINE ; DIAGNOSIS
英文摘要

Three patients with spinal primary diffuse-type tenosynovial giant cell tumor (DTGCT) received surgical treatment in our department between 2002 and 2012. All 3 patients were female and aged 23, 33, and 44 years. The mean time from symptom onset to diagnosis was 17 months (range, 5-24 months). One case involved the Cl right lateral mass and C2 vertebral body, the second involved the C1-2 left lateral masses and C2 vertebral body, and the third involved the C5-7 left lateral mass and C6 vertebral body. All patients underwent computed tomography-guided biopsy to confirm the diagnosis of tenosynovial giant cell tumor. Gross total resection was achieved in all patients, including 2 piecemeal resections and 1 en-bloc resection. The mean follow-up time was 6 years (range, 1-11 years), and there was no sign of recurrence in the patients. Seventy cases have been identified so far in the English literature. The male to female ratio is 1:1.38. The mean patient age is 38.5 +/- 17.9 years. The tumor distribution includes 32 cases in the cervical spine, 14 in the thoracic spine, 22 in the lumbar spine, and 1 in the sacrococcygeal region. The recurrence rate for patients who underwent gross total resection was 7.7%, and tumor progression was observed in 66.7% of patients who underwent subtotal resection. Above all, DTGCT is a rare primary spinal neoplasm. Preoperative image-guided biopsies play an important role in the diagnosis and treatment strategy. Gross total resection is the best treatment strategy and can reduce the recurrence rate.

语种英语
WOS记录号WOS:000343531700034
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62749
专题北京大学第三临床医学院_骨科
北京大学基础医学院
作者单位1.Peking Univ, Hosp 3, Dept Orthopaed, Beijing 100871, Peoples R China
2.Peking Univ, Hlth & Sci Ctr, Dept Pathol, Beijing 100871, Peoples R China
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GB/T 7714
Wang, Kai,Zhu, Bin,Yang, Shaomin,et al. Primary Diffuse-Type Tenosynovial Giant Cell Tumor of the Spine: A Report of 3 Cases and Systemic Review of the Literature[J]. TURKISH NEUROSURGERY,2014,24(5):804-813.
APA Wang, Kai,Zhu, Bin,Yang, Shaomin,Liu, Zhongjun,Yu, Miao,&Liu, Xiaoguang.(2014).Primary Diffuse-Type Tenosynovial Giant Cell Tumor of the Spine: A Report of 3 Cases and Systemic Review of the Literature.TURKISH NEUROSURGERY,24(5),804-813.
MLA Wang, Kai,et al."Primary Diffuse-Type Tenosynovial Giant Cell Tumor of the Spine: A Report of 3 Cases and Systemic Review of the Literature".TURKISH NEUROSURGERY 24.5(2014):804-813.
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