IR@PKUHSC  > 北京大学基础医学院  > 生物物理学系
学科主题基础医学
A study of hemorheological behaviour for patients with Alzheimer′s disease at the early stages
Wen, ZY; Xie, JX; Guan, ZW; Sun, DG; Yao, WJ; Chen, K; Yan, Z; Mu, QW
关键词blood viscosity Alzheimer&prime s disease hemorheology
刊名CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
2000
22期:4页:261-266
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Hematology ; Peripheral Vascular Disease
研究领域[WOS]Hematology ; Cardiovascular System & Cardiology
关键词[WOS]HIPPOCAMPAL-FORMATION ; ATROPHY ; MRI
英文摘要

To evaluate the change of hemorheological indexes for patients with Alzheimer′s disease (AD) at the early stages and to discuss effects of these changes on AD, high shear value of whole blood viscosity (eta(bh)), reduced high shear value of whole blood viscosity (r eta(bh)), low shear value of whole blood viscosity (eta(bl)), reduced low shear, value of whole blood viscosity (r eta(bl)), KT value of whole blood viscosity, hematocrit (HCT) and blood plasma viscosity (eta(P)) were measured in 31 patients with probable AD at the early stages and 33 age-matched healthy subjects. There were significant differences of all hemorheological indexes between AD group and control group except HCT. Step discriminant analysis revealed 81.25% of overall group-classified accuracy in a hemorheological discriminant function consisting of eta(bl), r eta(bl), r eta(bh) and HCT. Significant difference of hemorheological indexes existed between AD and age-matched healthy control subjects. The results showed that measurement of hemorheological indexes could be used as one of reference standards of diagnosis in AD.

语种英语
WOS记录号WOS:000089546400002
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62766
专题北京大学基础医学院_生物物理学系
作者单位1.Beijing Med Univ, Dept Med Phys, Beijing 100083, Peoples R China
2.Beijing Med Univ, Hosp 3, Dept Radiol, Beijing 100083, Peoples R China
3.Beijing Med Univ, Anal Ctr, Beijing 100083, Peoples R China
4.Peking Univ, Dept Engn Sci & Mech, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Wen, ZY,Xie, JX,Guan, ZW,et al. A study of hemorheological behaviour for patients with Alzheimer′s disease at the early stages[J]. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION,2000,22(4):261-266.
APA Wen, ZY.,Xie, JX.,Guan, ZW.,Sun, DG.,Yao, WJ.,...&Mu, QW.(2000).A study of hemorheological behaviour for patients with Alzheimer′s disease at the early stages.CLINICAL HEMORHEOLOGY AND MICROCIRCULATION,22(4),261-266.
MLA Wen, ZY,et al."A study of hemorheological behaviour for patients with Alzheimer′s disease at the early stages".CLINICAL HEMORHEOLOGY AND MICROCIRCULATION 22.4(2000):261-266.
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