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学科主题: 口腔医学
题名:
Biologic Agents for Periodontal Regeneration and Implant Site Development
作者: Suarez-Lopez del Amo, Fernando1; Monje, Alberto1; Padial-Molina, Miguel2; Tang, ZhiHui3; Wang, Hom-Lay1
刊名: BIOMED RESEARCH INTERNATIONAL
发表日期: 2015
DOI: 10.1155/2015/957518
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Biotechnology & Applied Microbiology ; Medicine, Research & Experimental
研究领域[WOS]: Biotechnology & Applied Microbiology ; Research & Experimental Medicine
关键词[WOS]: GROWTH-FACTOR-BB ; MAXILLARY SINUS AUGMENTATION ; PLATELET-RICH PLASMA ; BETA-TRICALCIUM PHOSPHATE ; HEALING FOLLOWING IMPLANTATION ; BONE MORPHOGENETIC PROTEIN-2 ; CONTROLLED CLINICAL-TRIAL ; CORONALLY ADVANCED FLAPS ; II FURCATION DEFECTS ; INTRABONY DEFECTS
英文摘要:

The advancement of molecular mediators or biologic agents has increased tremendously during the last decade in periodontology and dental implantology. Implant site development and reconstruction of the lost periodontium represent main fields in which these molecular mediators have been employed and investigated. Different growth factors trigger different reactions in the tissues of the periodontium at various cellular levels. Proliferation, migration, and differentiation constitute the main target areas of these molecular mediators. It was the purpose of this comprehensive review to describe the origin and rationale, evidence, and the most current understanding of the following biologic agents: Recombinant Human Platelet-Derived Growth Factor-BB (rhPDGF-BB), Enamel Matrix Derivate (EMD), Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF), Recombinant Human Fibroblast Growth Factor-2 (rhFGF-2), Bone Morphogenic Proteins (BMPs, BMP-2 and BMP-7), Teriparatide PTH, and Growth Differential Factor-5 (GDF-5).

语种: 英语
项目资助者: University of Michigan Periodontal Graduate Student Research Fund
WOS记录号: WOS:000363173600001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62776
Appears in Collections:北京大学口腔医学院_期刊论文

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作者单位: 1.Univ Granada, Dept Oral Surg & Implant Dent, Granada, Spain
2.Univ Michigan, Sch Dent, Dept Periodont & Oral Med, Ann Arbor, MI 48109 USA
3.Peking Univ, Sch Stomatol, Clin Div 2, Beijing 100871, Peoples R China

Recommended Citation:
Suarez-Lopez del Amo, Fernando,Monje, Alberto,Padial-Molina, Miguel,et al. Biologic Agents for Periodontal Regeneration and Implant Site Development[J]. BIOMED RESEARCH INTERNATIONAL,2015.
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