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学科主题: 临床医学
题名:
Ovarian suppression treatment prior to in-vitro fertilization and embryo transfer in Chinese women with stage III or IV endometriosis
作者: Ma, Caihong; Qiao, Jie; Liu, Ping; Chen, Guian
关键词: gonadotropin-releasing hormone agonist ; endometriosis ; in-vitro fertilization and ; embryo transfer
刊名: INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
发表日期: 2008-02-01
DOI: 10.1016/j.ijgo.2007.08.021
卷: 100, 期:2, 页:167-170
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Obstetrics & Gynecology
研究领域[WOS]: Obstetrics & Gynecology
英文摘要:

Objective: To evaluate the efficacy of a 2-month treatment with a gonadotropin-releasing hormone (GnRH) agonist prior to in-vitro fertilization in Chinese women with moderate or severe endometriosis. Methods: A study of 162 women surgically diagnosed as having moderate or severe endometriosis. Pituitary down-regulation was achieved with injections of a GnRH agonist prior to the IVF procedures either for 7 to 10 days in the mid-luteal phase (group 1 [standard protocol], 97 cycles in total), or for 2 months (group 2, 55 cycles), or 3 months (group 3, 75 cycles). Results: Women pretreated with a GnRH agonist for 2 or 3 months required significantly higher doses of gonadotropin for ovarian stimulation (P < 0.001), and for a longer time, than those treated with the standard long protocol (P < 0.05). The number of oocytes and good embryos was lower in group 3 than in groups 1 or 2 (P < 0.05). The implantation rate was significantly higher in group 2 than in group 1 (P < 0.02). Conclusion: A 2-month treatment with a GnRH agonist prior to IVF produced a trend toward an increase in the implantation rate in a group of Chinese women with stages III and IV endometriosis. (c) 2007 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

语种: 英语
WOS记录号: WOS:000253026000014
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62803
Appears in Collections:北京大学第三临床医学院_生殖医学中心_期刊论文

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作者单位: Peking Univ, Hosp 3, Ctr Reprod Med, Dept Obstet & Gynecol, Beijing, Peoples R China

Recommended Citation:
Ma, Caihong,Qiao, Jie,Liu, Ping,et al. Ovarian suppression treatment prior to in-vitro fertilization and embryo transfer in Chinese women with stage III or IV endometriosis[J]. INTERNATIONAL JOURNAL OF GYNECOLOGY &amp; OBSTETRICS,2008,100(2):167-170.
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