IR@PKUHSC  > 北京大学基础医学院  > 心血管所
学科主题基础医学
PPAR-delta in Vascular Pathophysiology
Wang, Nanping1,2
刊名PPAR RESEARCH
2008
DOI10.1155/2008/164163
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Medicine, Research & Experimental
研究领域[WOS]Research & Experimental Medicine
英文摘要

Peroxisome proliferator-activated receptors belong to the superfamily of ligand-dependent nuclear receptor transcription factors, which include three subtypes: PPAR-alpha, beta/delta, and gamma. PPAR-delta, play important roles in the regulation of cell growth and differentiation as well as tissue wound and repair. Emerging evidence has also demonstrated that PPAR-delta is implicated in lipids and glucose metabolism. Most recently, the direct effects of PPAR-delta on cardiovascular processes such as endothelial function and angiogenesis have also been investigated. Therefore, it is suggested that PPAR-delta may have critical roles in cardiovascular pathophysiology and is a potential target for therapeutic intervention of cardiovascular disorders such as atherosclerosis. Copyright (C) 2008 Nanping Wang.

语种英语
WOS记录号WOS:000207688600001
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被引频次:24[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62810
专题北京大学基础医学院_心血管所
北京大学基础医学院
作者单位1.Peking Univ, Hlth Sci Ctr, Lab Vasc Mol Biol & Bioengn, Inst Cardiovasc Sci, Beijing 100191, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Ctr Diabet, Beijing 100191, Peoples R China
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Wang, Nanping. PPAR-delta in Vascular Pathophysiology[J]. PPAR RESEARCH,2008.
APA Wang, Nanping.(2008).PPAR-delta in Vascular Pathophysiology.PPAR RESEARCH.
MLA Wang, Nanping."PPAR-delta in Vascular Pathophysiology".PPAR RESEARCH (2008).
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