北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第二临床医学院  > 期刊论文
学科主题: 临床医学
题名:
Bone marrow stromal cells differentiated into functional Schwann cells in injured rats sciatic nerve
作者: Zhang, PX; He, XJ; Liu, KY; Zhao, FQ; Fu, ZG; Zhang, DY; Zhang, Q; Jiang, BG
关键词: bone marrow stromal cells ; differentiation ; Schwann cells
刊名: ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY
发表日期: 2004
DOI: 10.1081/LABB-200039608
卷: 32, 期:4, 页:509-518
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biotechnology & Applied Microbiology ; Engineering, Biomedical ; Materials Science, Biomaterials
研究领域[WOS]: Biotechnology & Applied Microbiology ; Engineering ; Materials Science
关键词[WOS]: STEM-CELLS ; IN-VITRO ; REGENERATION ; TRANSPLANTATION ; ENGRAFTMENT ; BRAINS
英文摘要:

Bone marrow stromal cells (MSCs) have been shown to differentiate into various lineage cells including neural cells in vitro and in vivo. We therefore examined whether MSCs can differentiate into Schwann cells in injured peripheral nerves. After cultured in vitro, PKH-67-labeled MSCs were injected into the mechanically injured rat sciatic nerves. Three weeks after injection, immunofluorescent examinations were carried out. MSCs had been incorporated around the injured nerves and differentiated into Schwann cells. MSCs had accumulated mainly in the epineurium around the injured nerve. The incorporated cells partially expressed GFAP, S-100, and P75. These results confirmed the possibility that MSCs have the ability to differentiate into Schwann cells, and that injection of MSCs into the injured peripheral nerve would help repair damaged nerve.

语种: 英语
WOS记录号: WOS:000225928600003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62879
Appears in Collections:北京大学第二临床医学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Coll Med, People Hosp, Traumat Bone Dept, Beijing 100044, Peoples R China

Recommended Citation:
Zhang, PX,He, XJ,Liu, KY,et al. Bone marrow stromal cells differentiated into functional Schwann cells in injured rats sciatic nerve[J]. ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY,2004,32(4):509-518.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhang, PX]'s Articles
[He, XJ]'s Articles
[Liu, KY]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhang, PX]‘s Articles
[He, XJ]‘s Articles
[Liu, KY]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace