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The risk of melamine-induced nephrolithiasis in young children starts at a lower intake level than recommended by the WHO
Li, Gang1,2; Jiao, Shufang2; Yin, Xiangjun2; Deng, Ying2; Pang, Xinghuo2; Wang, Yan1
关键词Children Melamine Nephrolithiasis Tolerable daily intake Risk factor WHO
刊名PEDIATRIC NEPHROLOGY
2010
DOI10.1007/s00467-009-1298-3
25期:1页:135-141
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Pediatrics ; Urology & Nephrology
研究领域[WOS]Pediatrics ; Urology & Nephrology
关键词[WOS]HONG-KONG ; DISEASE
英文摘要

We investigated 683 children with nephrolithiasis and 6,498 children without nephrolithiasis aged < 3 years. Nephrolithiasis was diagnosed by renal ultrasonography in hospitals in Beijing in September/October 2008. In addition, data was collected on current and past formula feeding and on other possible risk factors for nephrolithiasis. Daily intake of melamine per kilogram of body weight was calculated for each individual. In general, the adjusted odds ratios between melamine dose and nephrolithiasis increased with an increasing daily level of melamine intake per kilogram of body weight. The risk of nephrolithiasis also increased with the increasing duration of exposure. Preterm infants, urinary malformation, and parents with a history of urinary stones were independent risk factors. In children exposed to melamine levels < 0.2 mg/kg per day, the adjusted odds ratio expressing the risk for nephrolithiasis was still 1.7 times higher than in those without melamine exposure. These findings suggest that the risk of melamine-induced nephrolithiasis in young children starts at a lower intake level than the levels recommended by the World Health Organization.

语种英语
WOS记录号WOS:000271961000016
引用统计
被引频次:23[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62882
专题北京大学公共卫生学院
作者单位1.Peking Univ, Sch Publ Hlth, Beijing 100191, Peoples R China
2.Beijing Ctr Dis Prevent & Control, Beijing 100013, Peoples R China
推荐引用方式
GB/T 7714
Li, Gang,Jiao, Shufang,Yin, Xiangjun,et al. The risk of melamine-induced nephrolithiasis in young children starts at a lower intake level than recommended by the WHO[J]. PEDIATRIC NEPHROLOGY,2010,25(1):135-141.
APA Li, Gang,Jiao, Shufang,Yin, Xiangjun,Deng, Ying,Pang, Xinghuo,&Wang, Yan.(2010).The risk of melamine-induced nephrolithiasis in young children starts at a lower intake level than recommended by the WHO.PEDIATRIC NEPHROLOGY,25(1),135-141.
MLA Li, Gang,et al."The risk of melamine-induced nephrolithiasis in young children starts at a lower intake level than recommended by the WHO".PEDIATRIC NEPHROLOGY 25.1(2010):135-141.
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