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学科主题: 公共卫生
题名:
The risk of melamine-induced nephrolithiasis in young children starts at a lower intake level than recommended by the WHO
作者: Li, Gang1,2; Jiao, Shufang2; Yin, Xiangjun2; Deng, Ying2; Pang, Xinghuo2; Wang, Yan1
关键词: Children ; Melamine ; Nephrolithiasis ; Tolerable daily intake ; Risk factor ; WHO
刊名: PEDIATRIC NEPHROLOGY
发表日期: 2010
DOI: 10.1007/s00467-009-1298-3
卷: 25, 期:1, 页:135-141
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pediatrics ; Urology & Nephrology
研究领域[WOS]: Pediatrics ; Urology & Nephrology
关键词[WOS]: HONG-KONG ; DISEASE
英文摘要:

We investigated 683 children with nephrolithiasis and 6,498 children without nephrolithiasis aged < 3 years. Nephrolithiasis was diagnosed by renal ultrasonography in hospitals in Beijing in September/October 2008. In addition, data was collected on current and past formula feeding and on other possible risk factors for nephrolithiasis. Daily intake of melamine per kilogram of body weight was calculated for each individual. In general, the adjusted odds ratios between melamine dose and nephrolithiasis increased with an increasing daily level of melamine intake per kilogram of body weight. The risk of nephrolithiasis also increased with the increasing duration of exposure. Preterm infants, urinary malformation, and parents with a history of urinary stones were independent risk factors. In children exposed to melamine levels < 0.2 mg/kg per day, the adjusted odds ratio expressing the risk for nephrolithiasis was still 1.7 times higher than in those without melamine exposure. These findings suggest that the risk of melamine-induced nephrolithiasis in young children starts at a lower intake level than the levels recommended by the World Health Organization.

语种: 英语
WOS记录号: WOS:000271961000016
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62882
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.Peking Univ, Sch Publ Hlth, Beijing 100191, Peoples R China
2.Beijing Ctr Dis Prevent & Control, Beijing 100013, Peoples R China

Recommended Citation:
Li, Gang,Jiao, Shufang,Yin, Xiangjun,et al. The risk of melamine-induced nephrolithiasis in young children starts at a lower intake level than recommended by the WHO[J]. PEDIATRIC NEPHROLOGY,2010,25(1):135-141.
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