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学科主题基础医学
Electroacupuncture of 2 Hz Has a Rewarding Effect: Evidence from a Conditioned Place Preference Study in Rats
Xia, Wei; Chu, Ning-Ning; Liang, Jing; Li, Yi-Jing; Zhang, Rong; Han, Ji-Sheng; Cui, Cai-Lian1
刊名EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
2011
DOI10.1093/ecam/nen043
4
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Integrative & Complementary Medicine
研究领域[WOS]Integrative & Complementary Medicine
关键词[WOS]BEHAVIORAL SENSITIZATION ; IDENTIFIED FREQUENCIES ; OPIOID-RECEPTORS ; STIMULATION ; MORPHINE ; EXPRESSION ; HEROIN ; MICE ; INVOLVEMENT ; ANTAGONISTS
英文摘要

Electroacupuncture (EA) has been used to suppress heroin craving in addicts and the conditioned place preference (CPP) for morphine in the rat.tempspacetempspace The question remained whether EA by itself will produce some rewarding effect.tempspacetempspace This was investigated using the CPP procedure in the present study.tempspacetempspaceThe results indicated that rats showed a significant preference to the 2Hz EA-paired compartment.tempspacetempspaceThis rewarding effect of EA was prevented by pre-treatment with the opioid receptor antagonist naloxone [2 mg kg(-1), intraperitoneally (i.p.)], CB1 cannabinoid antagonist AM251 (3 mu g per rat, intracerebroventricularly) or D1 dopamine receptor antagonist SCH23390 (0.1 mg kg(-1), i.p.), respectively. TempspacetempspaceIt is concluded that 2 Hz EA is capable of inducing CPP in the rat via the activation of the endogenous opioid-, cannabinoid- and dopamine- systems.

语种英语
WOS记录号WOS:000295672300001
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62884
Collection北京大学基础医学院_神经生物学系
作者单位1.Minist Educ, Key Lab Neurosci, Beijing 100191, Peoples R China
2.Minist Publ Hlth, Key Lab Neurosci, Beijing 100191, Peoples R China
3.Peking Univ, Dept Neurobiol, Neurosci Res Inst, Sch Basic Med Sci, Beijing 100191, Peoples R China
Recommended Citation
GB/T 7714
Xia, Wei,Chu, Ning-Ning,Liang, Jing,et al. Electroacupuncture of 2 Hz Has a Rewarding Effect: Evidence from a Conditioned Place Preference Study in Rats[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2011(4).
APA Xia, Wei.,Chu, Ning-Ning.,Liang, Jing.,Li, Yi-Jing.,Zhang, Rong.,...&Cui, Cai-Lian.(2011).Electroacupuncture of 2 Hz Has a Rewarding Effect: Evidence from a Conditioned Place Preference Study in Rats.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE(4).
MLA Xia, Wei,et al."Electroacupuncture of 2 Hz Has a Rewarding Effect: Evidence from a Conditioned Place Preference Study in Rats".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE .4(2011).
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