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IR@PKUHSC  > 北京大学临床肿瘤学院  > 期刊论文
学科主题: 临床医学
题名:
Molecular profiling of hepatocellular carcinomas by cDNA microarray
作者: Zhang, Lian-Hai; Ji, Jia-Fu
关键词: Hepatocellular carcinomas ; cDNA microarray ; Gene expression profiling
刊名: WORLD JOURNAL OF GASTROENTEROLOGY
发表日期: 2005-01-28
卷: 11, 期:4, 页:463-468
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology
研究领域[WOS]: Gastroenterology & Hepatology
英文摘要:

Hepatocellular carcinoma (HCC) is one of the most common cancers in the world. Conventional diagnosis and treatment of this malignancy have been dismal and should be complemented by novel tools. The development and progress of HCC are believed to be caused by the accumulation of genetic changes resulting in altered expression of thousands of cancer-related genes, which can be measured by globe genetic analysis. Gene expression profiling of HCC has been employed to elucidate hepatocarcinogenesis and disclose molecular mechanisms underlying complex clinical features. Identifying phenotype-associated genes/profiles has impacts on current diagnosis and management strategy of HCC. In spite of some pitfalls of this technology and challenges in improving the research process, scrutinous validation of profiling data of HCC combined with other approaches will eventually benefit the patients. (C) 2005 The WJG Press and Elsevier Inc. All rights reserved.

语种: 英语
WOS记录号: WOS:000208099700001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62921
Appears in Collections:北京大学临床肿瘤学院_期刊论文

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作者单位: Peking Univ, Sch Oncol, Beijing Canc Hosp, Beijing Inst Canc Res, Beijing 100034, Peoples R China

Recommended Citation:
Zhang, Lian-Hai,Ji, Jia-Fu. Molecular profiling of hepatocellular carcinomas by cDNA microarray[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2005,11(4):463-468.
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