IR@PKUHSC  > 北京大学临床肿瘤学院
学科主题临床医学
Molecular profiling of hepatocellular carcinomas by cDNA microarray
Zhang, Lian-Hai; Ji, Jia-Fu
关键词Hepatocellular carcinomas cDNA microarray Gene expression profiling
刊名WORLD JOURNAL OF GASTROENTEROLOGY
2005-01-28
11期:4页:463-468
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
研究领域[WOS]Gastroenterology & Hepatology
英文摘要

Hepatocellular carcinoma (HCC) is one of the most common cancers in the world. Conventional diagnosis and treatment of this malignancy have been dismal and should be complemented by novel tools. The development and progress of HCC are believed to be caused by the accumulation of genetic changes resulting in altered expression of thousands of cancer-related genes, which can be measured by globe genetic analysis. Gene expression profiling of HCC has been employed to elucidate hepatocarcinogenesis and disclose molecular mechanisms underlying complex clinical features. Identifying phenotype-associated genes/profiles has impacts on current diagnosis and management strategy of HCC. In spite of some pitfalls of this technology and challenges in improving the research process, scrutinous validation of profiling data of HCC combined with other approaches will eventually benefit the patients. (C) 2005 The WJG Press and Elsevier Inc. All rights reserved.

语种英语
WOS记录号WOS:000208099700001
引用统计
被引频次:22[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62921
专题北京大学临床肿瘤学院
北京大学临床肿瘤学院_胃肠肿瘤中心一病区
作者单位Peking Univ, Sch Oncol, Beijing Canc Hosp, Beijing Inst Canc Res, Beijing 100034, Peoples R China
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GB/T 7714
Zhang, Lian-Hai,Ji, Jia-Fu. Molecular profiling of hepatocellular carcinomas by cDNA microarray[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2005,11(4):463-468.
APA Zhang, Lian-Hai,&Ji, Jia-Fu.(2005).Molecular profiling of hepatocellular carcinomas by cDNA microarray.WORLD JOURNAL OF GASTROENTEROLOGY,11(4),463-468.
MLA Zhang, Lian-Hai,et al."Molecular profiling of hepatocellular carcinomas by cDNA microarray".WORLD JOURNAL OF GASTROENTEROLOGY 11.4(2005):463-468.
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