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学科主题: 口腔医学
题名:
Selective versus comprehensive neck dissection in the treatment of patients with a pathologically node-positive neck with or without microscopic extracapsular spread in oral squamous cell carcinoma
作者: Feng, Z.1; Gao, Y.2; Niu, L. X.1; Peng, X.1; Guo, C. B.1
关键词: oral squamous cell carcinoma ; selective neck dissection ; comprehensive neck dissection ; microscopic extracapsular spread ; prognosis ; complication
刊名: INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
发表日期: 2014-10-01
DOI: 10.1016/j.ijom.2014.05.018
卷: 43, 期:10, 页:1182-1188
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Dentistry, Oral Surgery & Medicine ; Surgery
研究领域[WOS]: Dentistry, Oral Surgery & Medicine ; Surgery
关键词[WOS]: SUPRAOMOHYOID NECK ; METASTASES ; MANAGEMENT ; RATIONALE ; TONGUE ; MOUTH ; FLOOR ; HEAD
英文摘要:

The objective of this study was to compare the prognosis and complications between selective neck dissection (SND) and comprehensive neck dissection (CND) for patients with a pathologically node-positive neck in squamous cell carcinoma of the tongue and the floor of the mouth. This was a retrospective cohort study. There was no significant difference between the SND group and the CND group in 3-year neck control rate (86.2% vs. 85.9%, P = 0.797) or disease-specific survival (DSS) rate (64.6% vs. 61.9%, P = 0.646). Further analyses of the respective 3-year DSS rates in the SND and CND subgroups were as follows: pN1 without extracapsular spread (ECS), 67.7% vs. 72.2%, P = 0.851; pN2b without ECS, 64.7% vs. 68.8%, P = 0.797; and pN+ with ECS, 57.1% vs. 60.0%, P = 0.939. Of note, there were significantly fewer complications in the SND group compared with the CND group (7.3% vs. 20.0%, P = 0.032). Multivariate analysis showed that the modality of neck treatment, pN+ status, and microscopic ECS did not serve as independent prognostic factors. SND plus adjuvant radiotherapy is a management strategy of high efficiency and minor morbidity for selected oral cancer patients with a pN+ neck with or without microscopic ECS.

语种: 英语
所属项目编号: 81302350 ; 7144258 ; 2013M530495 ; 2009AA045201
项目资助者: National Natural Science Foundation of China ; Beijing Municipal Natural Science Foundation ; China Postdoctoral Science Foundation ; National High Technology Research and Development Program of China
WOS记录号: WOS:000343389800003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/62929
Appears in Collections:北京大学口腔医学院_期刊论文

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作者单位: 1.Peking Univ, Sch Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100081, Peoples R China
2.Peking Univ, Sch Stomatol, Dept Pathol, Beijing 100081, Peoples R China

Recommended Citation:
Feng, Z.,Gao, Y.,Niu, L. X.,et al. Selective versus comprehensive neck dissection in the treatment of patients with a pathologically node-positive neck with or without microscopic extracapsular spread in oral squamous cell carcinoma[J]. INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY,2014,43(10):1182-1188.
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