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学科主题临床医学
Fourier transform mid-infrared spectroscopy (FTIR) used for the rapid intraoperative diagnosis of gallbladder diseases
Xu Yi-Zhuang; Zhao Ying; Ling Xiao-Feng; Yang Li-Min; Xu Zhi; Zhou Xiao-Si; Zhang Yuan-Fu; Gong Rong-Ye; Pan Qing-Hua; Wang Bing-Bing; Shi Jing-Sen; Xu Duan-Fu; Wu Jin-Guang
关键词FTIR mid-IR fiber optics gallbladder detection
刊名CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
2007-04-10
28期:4页:645-648
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]IN-VIVO ; TUMOR
英文摘要

Identification of gallbladder cancer rapidly at the time of surgery would allow the appropriate resection to be completed at the original surgery. The aim of this study was to assess the sensitivity and specificity of FTIR in the rapid detection of gallbladder cancer, via an attenuated total reflection( ATR ) accessory with a ZnSe window. This allowed the edges of the surgically resected specimens to be examined rapidly. The results indicate that there are a series of differences between the spectra of normal and malignant tissues, and subtraction technique is helpful to identify cholecystitis and gallbladder cancer. Compared with pathological diagnosis results, one benign specimen was classified as a malignant and 6/6 malignant specimens and 39 cases of benign specimens were correctly classified. The sensitivity was 100% ( 6/6 ), specificity 97% ( 39/40 ), and accuracy was 97% ( 45/46 ). We can conclude that mid-infrared ATR FTIR spectroscopy is highly accurate and rapidly allows appropriately tailored resection at the time of initial surgery.

语种中文
WOS记录号WOS:000245874300010
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62934
专题北京大学第三临床医学院_普通外科
作者单位1.Peking Univ, Dept Surg, Hosp 3, Beijing 100083, Peoples R China
2.Hangzhou Teachers Coll, Hangzhou 310015, Peoples R China
3.Second People Hosp Hangzhou, Hangzhou 310015, Peoples R China
4.Peking Univ, Coll Chem & Mol Engn, State Key Lab Rare Earth Mat & Applicat, Beijing 100871, Peoples R China
5.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
6.Beijing Rayleigh Analyt Instrument Corp, Beijing Opt Instrument Factory 2, Beijing 100015, Peoples R China
7.Xian Jiaotong Univ, Dept Surg Oncol, Hosp 1, Xian 710061, Peoples R China
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Xu Yi-Zhuang,Zhao Ying,Ling Xiao-Feng,et al. Fourier transform mid-infrared spectroscopy (FTIR) used for the rapid intraoperative diagnosis of gallbladder diseases[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2007,28(4):645-648.
APA Xu Yi-Zhuang.,Zhao Ying.,Ling Xiao-Feng.,Yang Li-Min.,Xu Zhi.,...&Wu Jin-Guang.(2007).Fourier transform mid-infrared spectroscopy (FTIR) used for the rapid intraoperative diagnosis of gallbladder diseases.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,28(4),645-648.
MLA Xu Yi-Zhuang,et al."Fourier transform mid-infrared spectroscopy (FTIR) used for the rapid intraoperative diagnosis of gallbladder diseases".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 28.4(2007):645-648.
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