| 学科主题 | 临床医学 |
| Allergenic and antigenic activity of cow milk substitutes by ELISA and basophil-activation assays | |
| Lou, F.1; Cong, Y. J.2; Ibrahim, Salam A.3; Ren, F. Z.1; Li, L. F.4 | |
| 关键词 | allergenicity antigenicity cow milk substitute |
| 刊名 | FOOD AND AGRICULTURAL IMMUNOLOGY
 |
| 2010 | |
| DOI | 10.1080/09540100903443709 |
| 卷 | 21期:2页:119-130 |
| 收录类别 | SCI |
| 文章类型 | Article |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Chemistry, Applied ; Food Science & Technology ; Immunology ; Toxicology |
| 资助者 | National Science and Technology Supporting Item (China) ; National Science and Technology Supporting Item (China) |
| 研究领域[WOS] | Chemistry ; Food Science & Technology ; Immunology ; Toxicology |
| 关键词[WOS] | IN-VITRO ; PROTEINS ; IGE ; HYDROLYSIS ; ARA-H-1 ; POTENCY |
| 英文摘要 | We conducted enzyme-linked immunosorbent assay (ELISA) and basophil-activation assay in order to investigate the presence of allergens in selected cow milk (CM) substitutes. Our results showed the presence of residual antigenicity and allergenicity. The cross-reactivity between proteins from different animal species was observed. CM allergen-induced histamine release was dose-dependent. Therefore, differences in the relative percentage of major allergens may lead to a discrepancy between allergenic and antigenic activity. The presence of very similar epitopes could explain the cross-reactivity in mammalian milks. |
| 语种 | 英语 |
| 资助者 | National Science and Technology Supporting Item (China) ; National Science and Technology Supporting Item (China) |
| WOS记录号 | WOS:000277487500004 |
| Citation statistics | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.bjmu.edu.cn/handle/400002259/62963 |
| Collection | 北京大学第三临床医学院_皮肤科 |
| 作者单位 | 1.China Agr Univ, Coll Food Sci & Nutr Engn, Beijing 100083, Peoples R China 2.Beijing Technol & Business Univ, Coll Chem & Environm Engn, Beijing 100048, Peoples R China 3.N Carolina Agr & Tech State Univ, Food Microbiol & Biotechnol Lab, Greensboro, NC 27411 USA 4.Peking Univ, Hosp 3, Dept Dermatol, Beijing 100083, Peoples R China |
| Recommended Citation GB/T 7714 | Lou, F.,Cong, Y. J.,Ibrahim, Salam A.,et al. Allergenic and antigenic activity of cow milk substitutes by ELISA and basophil-activation assays[J]. FOOD AND AGRICULTURAL IMMUNOLOGY,2010,21(2):119-130. |
| APA | Lou, F.,Cong, Y. J.,Ibrahim, Salam A.,Ren, F. Z.,&Li, L. F..(2010).Allergenic and antigenic activity of cow milk substitutes by ELISA and basophil-activation assays.FOOD AND AGRICULTURAL IMMUNOLOGY,21(2),119-130. |
| MLA | Lou, F.,et al."Allergenic and antigenic activity of cow milk substitutes by ELISA and basophil-activation assays".FOOD AND AGRICULTURAL IMMUNOLOGY 21.2(2010):119-130. |
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