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学科主题临床医学
Sulfur dioxide, a double-faced molecule in mammals
Wang, Xin-Bao1; Du, Jun-Bao2; Cui, Hong1
关键词Sulfur dioxide Physiological effects Pathophysiological effects Biology Gasotransmitter
刊名LIFE SCIENCES
2014-03-11
DOI10.1016/j.lfs.2013.12.027
98期:2页:63-67
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Medicine, Research & Experimental ; Pharmacology & Pharmacy
研究领域[WOS]Research & Experimental Medicine ; Pharmacology & Pharmacy
关键词[WOS]OXIDATIVE DAMAGE ; CARDIOVASCULAR-SYSTEM ; HYDROGEN-SULFIDE ; MICE ; INHALATION ; DERIVATIVES ; MODULATION ; INJURY ; RATS ; SO2
英文摘要

Sulfur dioxide (SO2) is a common air pollutant and is detrimental to many organs. Its toxic effects including oxidative damage, deoxyribonucleic acid (DNA) damage and inflammation have been extensively studied. However, recent studies showed that SO2 can be generated endogenously in mammals. In contrast to the toxic effects of SO2, protective effects have also been found in mammals. Endogenous SO2 has antioxidant, anti-inflammatory, anti-hypertension, and anti-atherogenic effects and regulates vascular tone and cardiac function in mammals. SO2 may have a dual role in regulating physiological and pathophysiological effects in manimals. The biological effects of SO2 in mammals are reviewed in this study. (c) 2014 Elsevier Inc. All rights reserved.

语种英语
WOS记录号WOS:000332443000001
引用统计
被引频次:30[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/62985
专题北京大学第一临床医学院_儿科
作者单位1.Capital Med Univ, Beijing Friendship Hosp, Dept Pediat, Beijing 100050, Peoples R China
2.Peking Univ, Hosp 1, Dept Pediat, Beijing 100034, Peoples R China
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GB/T 7714
Wang, Xin-Bao,Du, Jun-Bao,Cui, Hong. Sulfur dioxide, a double-faced molecule in mammals[J]. LIFE SCIENCES,2014,98(2):63-67.
APA Wang, Xin-Bao,Du, Jun-Bao,&Cui, Hong.(2014).Sulfur dioxide, a double-faced molecule in mammals.LIFE SCIENCES,98(2),63-67.
MLA Wang, Xin-Bao,et al."Sulfur dioxide, a double-faced molecule in mammals".LIFE SCIENCES 98.2(2014):63-67.
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