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学科主题: 临床医学
题名:
A cross-sectional study on upright heart rate and BP changing characteristics: basic data for establishing diagnosis of postural orthostatic tachycardia syndrome and orthostatic hypertension
作者: Zhao, Juan1; Han, Zhenhui2; Zhang, Xi2; Du, Shuxu3; Liu, Angie Dong4; Holmberg, Lukas4; Li, Xueying5; Lin, Jing1; Xiong, Zhenyu2; Gai, Yong2; Yang, Jinyan1; Liu, Ping1; Tang, Chaoshu6; Du, Junbao1,7; Jin, Hongfang1
刊名: BMJ OPEN
发表日期: 2015
DOI: 10.1136/bmjopen-2014-007356
卷: 5, 期:6
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: BLOOD-PRESSURE ; CHILDREN ; ADOLESCENTS ; INTOLERANCE ; TILT
英文摘要:

Objective: We aimed to determine upright heart rate and blood pressure (BP) changes to suggest diagnostic criteria for postural orthostatic tachycardia syndrome (POTS) and orthostatic hypertension (OHT) in Chinese children.

Methods: In this cross-sectional study, 1449 children and adolescents aged 6-18 years were randomly recruited from two cities in China, Kaifeng in Henan province and Anguo in Hebei province. They were divided into two groups: 844 children aged 6-12 years (group I) and 605 adolescents aged 13-18 years (group II). Heart rate and BP were recorded during an active standing test.

Results: 95th percentile (P-95) of delta heart rate from supine to upright was 38 bpm, with a maximum upright heart rate of 130 and 124 bpm in group I and group II, respectively. P-95 of delta systolic blood pressure (SBP) increase was 18 mm Hg and P-95 of upright SBP was 132 mm Hg in group I and 138 mm Hg in group II. P-95 of delta diastolic blood pressure (DBP) increase was 24 mm Hg in group I and 21 mm Hg in group II, and P-95 of upright DBP was 89 mm Hg in group I and 91 mm Hg in group II.

Conclusions: POTS is suggested when delta heart rate is >= 38 bpm (for easy memory, >= 40 bpm) from supine to upright, or maximum heart rate >= 130 bpm (children aged 6-12 years) and >= 125 bpm (adolescents aged 13-18 years), associated with orthostatic symptoms. OHT is suggested when delta SBP (increase) is >= 20 mm Hg, and/or delta DBP (increase) >= 25 mm Hg (in children aged 6-12 years) or >= 20 mm Hg (in adolescents aged 13-18 years) from supine to upright; or upright BP >= 130/90 mm Hg (in children aged 6-12 years) or >= 140/90 mm Hg (in adolescents aged 13-18 years).

语种: 英语
所属项目编号: 2012BAI03B03 ; 2012CB517806 ; 2011CB503904 ; 2012BA103B03 ; 81121061
项目资助者: National Twelfth Five-Year Plan for Science and Technology Support ; Major Basic Research Project of China ; National Natural Science Foundation of China
WOS记录号: WOS:000355551100015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63083
Appears in Collections:北京大学第一临床医学院_儿科_期刊论文

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作者单位: 1.Peking Univ, Hosp 1, Dept Pediat, Beijing 100871, Peoples R China
2.Kaifeng Childrens Hosp, Dept Pediat, Kaifeng, Henan, Peoples R China
3.Capital Med Univ, Shijitan Hosp, Dept Pediat, Beijing, Peoples R China
4.Linkoping Univ, Dept Med & Hlth Sci, Linkoping, Sweden
5.Minist Educ, Key Lab Cardiovasc Med, Beijing, Peoples R China
6.Peking Univ, Hosp 1, Dept Med Stat, Beijing 100871, Peoples R China
7.Peking Univ, Dept Physiol & Pathophysiol, Hlth Sci Ctr, Beijing 100871, Peoples R China

Recommended Citation:
Zhao, Juan,Han, Zhenhui,Zhang, Xi,et al. A cross-sectional study on upright heart rate and BP changing characteristics: basic data for establishing diagnosis of postural orthostatic tachycardia syndrome and orthostatic hypertension[J]. BMJ OPEN,2015,5(6).
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