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A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes
Li, Ruimin1; Zhen, Mingming1; Guan, Mirong1; Chen, Daiqin1; Zhang, Guoqiang1; Ge, Jiechao2; Gong, Ping3; Wang, Chunru1; Shu, Chunying1
关键词C-60-carboxyfullerenes Peroxidase-like activity Colorimetric sensor Glucose
刊名BIOSENSORS & BIOELECTRONICS
2013-09-15
DOI10.1016/j.bios.2013.03.057
47页:502-507
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biophysics ; Biotechnology & Applied Microbiology ; Chemistry, Analytical ; Electrochemistry ; Nanoscience & Nanotechnology
研究领域[WOS]Biophysics ; Biotechnology & Applied Microbiology ; Chemistry ; Electrochemistry ; Science & Technology - Other Topics
关键词[WOS]MAGNETIC NANOPARTICLES ; GRAPHENE OXIDE ; URINE GLUCOSE ; FULLERENE ; VISUALIZATION ; BIOCATALYSIS ; DERIVATIVES ; MIMETICS ; CHITOSAN ; ACID
英文摘要

C-60-carboxyfullerene, C-60[C(COOH)(2)](2), has been proven to function as peroxidase mimetics that can catalyze the reaction of peroxidase substrate 3,3′,5,5′-tetramethylbenzidine (TMB) in the presence of H2O2 to produce a blue color reaction. Kinetic studies further indicate that C-60[C(COOH)(2)](2) has an even higher affinity to TMB than that of the natural enzyme, horseradish peroxidase (HRP). C-60[C(COOH)(2)](2)/glucose oxidase (GO(x))/TMB system provides a novel colorimetric sensor for glucose and shows good response toward glucose detection over a range of 1.0-40 mu M with a limit of detection 0.5 mu M (3 sigma/slope). Moreover, this sensitive and selective sensor can be successfully applied for the quantitative determination of glucose in human serum. The results indicate that it is a simple, cheap, convenient, highly selective, sensitive, and easy handling colorimetric assay. (C) 2013 Elsevier B.V. All rights reserved.

语种英语
WOS记录号WOS:000320481900076
项目编号2011CB302100 ; 21121063 ; 91027018 ; 51172244 ; 11076027
资助机构973 Program ; National Natural Science Foundation of China ; NSAF
引用统计
被引频次:68[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63097
专题北京大学第三临床医学院
作者单位1.Peking Univ, Hosp 3, Beijing 100191, Peoples R China
2.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Mol Nanostruct & Nanotechnol, Inst Chem, Beijing 100190, Peoples R China
3.Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Li, Ruimin,Zhen, Mingming,Guan, Mirong,et al. A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes[J]. BIOSENSORS & BIOELECTRONICS,2013,47:502-507.
APA Li, Ruimin.,Zhen, Mingming.,Guan, Mirong.,Chen, Daiqin.,Zhang, Guoqiang.,...&Shu, Chunying.(2013).A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes.BIOSENSORS & BIOELECTRONICS,47,502-507.
MLA Li, Ruimin,et al."A novel glucose colorimetric sensor based on intrinsic peroxidase-like activity of C-60-carboxyfullerenes".BIOSENSORS & BIOELECTRONICS 47(2013):502-507.
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