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学科主题临床医学
Evaluating peritoneal fluid transport in continuous peritoneal dialysis patients: A practical approach
Zhe, Xing-Wei; Tian, Xin-Kui; Shan, Yi-Sheng; Cheng, Lei; Wang, Tao
关键词peritoneal dialysis fluid kinetics peritoneal fluid transport modeling
刊名NEPHRON CLINICAL PRACTICE
2007
DOI10.1159/000110031
107期:4页:C123-C127
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Urology & Nephrology
研究领域[WOS]Urology & Nephrology
关键词[WOS]CAPD
英文摘要

Background/Aims: Evaluating the peritoneal fluid kinetics is of clinical importance in peritoneal dialysis treatment. We have previously developed a simple way to evaluate the peritoneal fluid transport characteristics in continuous ambulatory peritoneal dialysis patients which, however, cannot be applied to those patients on a fixed dialysis schedule. Therefore, in the present study, we tested the possibility to vary the peritoneal dwell time and tried to develop a more patient-friendly ultrafiltration (UF) collection protocol. Methods: The patients′ UF volume was recorded for 10 days. All patients recruited were asked to perform their usual dialysis exchanges with, however, a special UF data collection protocol to improve the accuracy of computer simulation: at least one dwell of 2-4 h, one of 4-7 h, and one of more than 7 h. The fluid transport model was applied to the pooled UF volume for fluid kinetics simulation, and the data from the following day′s UF records using the same glucose concentration and dwell time were used to evaluate reliability and accuracy of the simulated UF value. Results: Fifty-two chronic peritoneal dialysis patients were included in the present study. All of the UF data could be used in the computer simulation, and there was a significant negative correlation between fluid absorption rate (K-e; see text) and actual UF volume on the following day using a glucose concentration of 1.5% and a dwell time of 4 h (r = -0.336, p < 0.05). The estimated UF values correlated significantly with the actually measured UF values. The variability of the results, expressed by the width between the 95% limits of agreement, fell within -139.2 to 131.9 ml, while the mean difference was -3.7 ml. Conclusions: Our present study showed that varying the peritoneal dwell time was a patient-friendly UF data collection protocol for continuous ambulatory peritoneal dialysis patients on a fixed dialysis schedule. Applying the fluid transport model and nonlinear least squares regression analysis to pooled UF values might be a good and simple way to predict the peritoneal UF capacity. Copyright (C) 2007 S. Karger AG, Basel.

语种英语
WOS记录号WOS:000251439000001
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63098
专题北京大学第三临床医学院_肾内科
作者单位Beijing Univ, Div Nephrol, Hosp 3, Beijing 100083, Peoples R China
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GB/T 7714
Zhe, Xing-Wei,Tian, Xin-Kui,Shan, Yi-Sheng,et al. Evaluating peritoneal fluid transport in continuous peritoneal dialysis patients: A practical approach[J]. NEPHRON CLINICAL PRACTICE,2007,107(4):C123-C127.
APA Zhe, Xing-Wei,Tian, Xin-Kui,Shan, Yi-Sheng,Cheng, Lei,&Wang, Tao.(2007).Evaluating peritoneal fluid transport in continuous peritoneal dialysis patients: A practical approach.NEPHRON CLINICAL PRACTICE,107(4),C123-C127.
MLA Zhe, Xing-Wei,et al."Evaluating peritoneal fluid transport in continuous peritoneal dialysis patients: A practical approach".NEPHRON CLINICAL PRACTICE 107.4(2007):C123-C127.
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