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学科主题: 药学
题名:
Synthesis of beta- and gamma-Carbolinones via Pd-Catalyzed Direct Dehydrogenative Annulation (DDA) of Indole-carboxamides with Alkynes Using Air as the Oxidant
作者: Shi, Zhuangzhi1; Cui, Yuxin1; Jiao, Ning1,2
刊名: ORGANIC LETTERS
发表日期: 2010-07-02
DOI: 10.1021/ol1007839
卷: 12, 期:13, 页:2908-2911
收录类别: SCI ; IC ; CCR
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Organic
研究领域[WOS]: Chemistry
关键词[WOS]: C-H ACTIVATION ; BOND FUNCTIONALIZATION ; INTERNAL ALKYNES ; OXIDATIVE CYCLIZATION ; AROMATIC SUBSTITUTION ; DERIVATIVES ; PALLADIUM(II) ; ARYLATION ; MULTIPLE ; ANILINES
英文摘要:

A palladium-catalyzed direct dehydrogenative annulation (DDA) of indolecarboxamides with internal alkynes via C-H and N-H bond cleavage using air as the oxidant was developed. With this method, both beta- and gamma-carbolinones can be easily prepared under the mild conditions.

语种: 英语
所属项目编号: 20702002 ; 20872003 ; 2009CB825300
项目资助者: Peking University ; National Science Foundation of China ; National Basic Research Program of China (973 Program)
WOS记录号: WOS:000279070100005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63105
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
2.E China Normal Univ, Dept Chem, Shanghai Key Lab Green Chem & Chem Proc, Shanghai 200062, Peoples R China

Recommended Citation:
Shi, Zhuangzhi,Cui, Yuxin,Jiao, Ning. Synthesis of beta- and gamma-Carbolinones via Pd-Catalyzed Direct Dehydrogenative Annulation (DDA) of Indole-carboxamides with Alkynes Using Air as the Oxidant[J]. ORGANIC LETTERS,2010,12(13):2908-2911.
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