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学科主题: 药学
题名:
Triterpenoid saponins from Ilex mamillata CY Wu ex CJ Tseng
作者: Che Yan-Yun1; Zhang Liang2; Li Ning2; Zeng Ke-Wu2; Tu Peng-Fei1,2
关键词: Ilex mamillata ; triterpenoid saponin ; ilemaminosides A and B
刊名: NATURAL PRODUCT RESEARCH
发表日期: 2012
DOI: 10.1080/14786419.2011.636744
卷: 26, 期:21, 页:1991-1995
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Applied ; Chemistry, Medicinal
研究领域[WOS]: Chemistry ; Pharmacology & Pharmacy
关键词[WOS]: PUBESCENS ; LEAVES
英文摘要:

Two new triterpenoid saponins, ilemaminosides A and B (1 and 2) along with six known saponins (3-8) were isolated from 70% ethanolic extract of the leaves of Ilex mamillata C.Y. Wu ex C.J. Tseng. The new saponins were characterised as 3-O-alpha-L-arabinopyranosyl-ilexgenin B (1) and 3-O-beta-D-glucopyranosyl-(1 -> 3)-alpha-L-arabinopyranosyl-ilexgenin B (2). The structures of compounds 1 and 2 were elucidated on the basis of the chemical and spectroscopic methods, and the structures of known compounds were identified by comparison of their spectroscopic data with those reported in the literature. The compounds showed inhibitory activities in anti-inflammatory assay in vitro with IC50 values in the range 25.37-38.33 mu gmL(-1).

语种: 英语
WOS记录号: WOS:000309287500006
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63111
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.China Pharmaceut Univ, Dept Pharmacognosy, Minist Educ, Key Lab Modern Chinese Med, Nanjing 210009, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

Recommended Citation:
Che Yan-Yun,Zhang Liang,Li Ning,et al. Triterpenoid saponins from Ilex mamillata CY Wu ex CJ Tseng[J]. NATURAL PRODUCT RESEARCH,2012,26(21):1991-1995.
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