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Triterpenoid saponins from Ilex mamillata CY Wu ex CJ Tseng
Che Yan-Yun1; Zhang Liang2; Li Ning2; Zeng Ke-Wu2; Tu Peng-Fei1,2
关键词Ilex mamillata triterpenoid saponin ilemaminosides A and B
刊名NATURAL PRODUCT RESEARCH
2012
DOI10.1080/14786419.2011.636744
26期:21页:1991-1995
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Applied ; Chemistry, Medicinal
研究领域[WOS]Chemistry ; Pharmacology & Pharmacy
关键词[WOS]PUBESCENS ; LEAVES
英文摘要

Two new triterpenoid saponins, ilemaminosides A and B (1 and 2) along with six known saponins (3-8) were isolated from 70% ethanolic extract of the leaves of Ilex mamillata C.Y. Wu ex C.J. Tseng. The new saponins were characterised as 3-O-alpha-L-arabinopyranosyl-ilexgenin B (1) and 3-O-beta-D-glucopyranosyl-(1 -> 3)-alpha-L-arabinopyranosyl-ilexgenin B (2). The structures of compounds 1 and 2 were elucidated on the basis of the chemical and spectroscopic methods, and the structures of known compounds were identified by comparison of their spectroscopic data with those reported in the literature. The compounds showed inhibitory activities in anti-inflammatory assay in vitro with IC50 values in the range 25.37-38.33 mu gmL(-1).

语种英语
WOS记录号WOS:000309287500006
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63111
专题北京大学药学院
北京大学药学院_天然药物学系
北京大学第三临床医学院_麻醉科
作者单位1.China Pharmaceut Univ, Dept Pharmacognosy, Minist Educ, Key Lab Modern Chinese Med, Nanjing 210009, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Che Yan-Yun,Zhang Liang,Li Ning,et al. Triterpenoid saponins from Ilex mamillata CY Wu ex CJ Tseng[J]. NATURAL PRODUCT RESEARCH,2012,26(21):1991-1995.
APA Che Yan-Yun,Zhang Liang,Li Ning,Zeng Ke-Wu,&Tu Peng-Fei.(2012).Triterpenoid saponins from Ilex mamillata CY Wu ex CJ Tseng.NATURAL PRODUCT RESEARCH,26(21),1991-1995.
MLA Che Yan-Yun,et al."Triterpenoid saponins from Ilex mamillata CY Wu ex CJ Tseng".NATURAL PRODUCT RESEARCH 26.21(2012):1991-1995.
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