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学科主题: 临床医学
题名:
Efficacy of local aspiration in the conservative treatment of live interstitial pregnancy coexisting with live intrauterine pregnancy after in vitro fertilization and embryo transfer
作者: Wang Yang; Ma Cai-hong; Qiao Jie; Chen Xin-na; Liu Ping
关键词: interstitial pregnancy ; heterotopic pregnancy ; fetocide ; in vitro fertilization ; transvaginal ultrasound-guided aspiration
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2012-04-05
DOI: 10.3760/cma.j.issn.0366-6999.2012.07.028
卷: 125, 期:7, 页:1345-1348
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: ECTOPIC PREGNANCY ; HETEROTOPIC PREGNANCY ; HYPEROSMOLAR GLUCOSE ; INSTILLATION ; MANAGEMENT
英文摘要:

Background Heterotopic pregnancy (HP) is defined as a pregnancy in which one or more embryos is viably implanted in the uterus while the other is implanted elsewhere as an ectopic pregnancy. The occurrence of HP rises dramatically with the increased use of assisted reproductive technology. HP of interstitial pregnancy is one special situation which needs more concern. Here we evaluate the efficacy of local aspiration and instillation of hyperosmolar glucose in the treatment of live interstitial pregnancy complicated with live intrauterine pregnancy after in vitro fertilization and embryo transfer.

Methods Five female patients were diagnosed with live interstitial pregnancies complicated with intrauterine pregnancies. They were treated with transvaginal ultrasound-guided aspiration of interstitial pregnancy and instillation of hyperosmolar glucose at the Center for Reproductive Medicine of Peking University Third Hospital from January 1st, 2008 to May 30th, 2011.

Results Gemmule embryos in all 5 cases were aspirated successfully and there was no abdominal hemorrhage, threatened abortion or infection in any of the cases. The sac of interstitial pregnancy continued to progress after aspiration and stopped growing between 11 to 20 weeks. By the 30th week of pregnancy, 80% of the interstitial masses had disappeared. Four cases have delivered and one is still in on-going pregnancy. All of the four cases underwent cesarean section and there were nothing special detected in the corner of the uterus.

Conclusion Local aspiration and instillation of hyperosmolar glucose may be an effective way to treat live interstitial pregnancy when coexisting with a live intrauterine pregnancy. Chin Med J 2012;125(7):1345-1348

语种: 英语
所属项目编号: 81170618
项目资助者: National Natural Science Foundation of China
WOS记录号: WOS:000302882600029
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63129
Appears in Collections:北京大学第三临床医学院_生殖医学中心_期刊论文

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作者单位: Peking Univ, Ctr Reprod Med, Hosp 3, Beijing 100191, Peoples R China

Recommended Citation:
Wang Yang,Ma Cai-hong,Qiao Jie,et al. Efficacy of local aspiration in the conservative treatment of live interstitial pregnancy coexisting with live intrauterine pregnancy after in vitro fertilization and embryo transfer[J]. CHINESE MEDICAL JOURNAL,2012,125(7):1345-1348.
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