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学科主题: 基础医学
题名:
Could circulating miRNAs contribute to cancer therapy?
作者: Chen, Geng1,2,3; Wang, Juan1,2,3; Cui, Qinghua1,2,3
关键词: microRNA ; biomarker ; cancer therapy
刊名: TRENDS IN MOLECULAR MEDICINE
发表日期: 2013-02-01
DOI: 10.1016/j.molmed.2012.10.006
卷: 19, 期:2, 页:71-73
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemistry & Molecular Biology ; Cell Biology ; Medicine, Research & Experimental
研究领域[WOS]: Biochemistry & Molecular Biology ; Cell Biology ; Research & Experimental Medicine
关键词[WOS]: MICRORNAS ; BIOMARKERS ; DISEASES
英文摘要:

The roles of circulating miRNAs in disease therapy remain largely unclear, but recent data suggests a role for these molecules in cancer. In patients with cancer, the levels of circulating miRNAs with tumor-suppressing capabilities increase and those with oncogenic activity decrease. In addition, the population of circulating miRNAs correlates highly with immune response, suggesting that circulating miRNAs could be driving anticancer effects through active immune defense and might be a novel strategy for cancer therapy.

语种: 英语
所属项目编号: 2012CB517500 ; 31000585 ; 81001481
项目资助者: National Basic Research program of China ; National Natural Science Foundation of China
WOS记录号: WOS:000315177900001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63130
Appears in Collections:基础医学院_北京大学系统生物医学研究所_期刊论文

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作者单位: 1.Peking Univ, Inst Syst Biomed, Beijing 100191, Peoples R China
2.Peking Univ, MOE Kay Lab Cardiovasc Sci, Beijing 100191, Peoples R China
3.Peking Univ, Dept Biomed Informat, Beijing 100191, Peoples R China

Recommended Citation:
Chen, Geng,Wang, Juan,Cui, Qinghua. Could circulating miRNAs contribute to cancer therapy?[J]. TRENDS IN MOLECULAR MEDICINE,2013,19(2):71-73.
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