学科主题基础医学
Could circulating miRNAs contribute to cancer therapy?
Chen, Geng1,2,3; Wang, Juan1,2,3; Cui, Qinghua1,2,3
关键词microRNA biomarker cancer therapy
刊名TRENDS IN MOLECULAR MEDICINE
2013-02-01
DOI10.1016/j.molmed.2012.10.006
19期:2页:71-73
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Cell Biology ; Medicine, Research & Experimental
研究领域[WOS]Biochemistry & Molecular Biology ; Cell Biology ; Research & Experimental Medicine
关键词[WOS]MICRORNAS ; BIOMARKERS ; DISEASES
英文摘要

The roles of circulating miRNAs in disease therapy remain largely unclear, but recent data suggests a role for these molecules in cancer. In patients with cancer, the levels of circulating miRNAs with tumor-suppressing capabilities increase and those with oncogenic activity decrease. In addition, the population of circulating miRNAs correlates highly with immune response, suggesting that circulating miRNAs could be driving anticancer effects through active immune defense and might be a novel strategy for cancer therapy.

语种英语
WOS记录号WOS:000315177900001
项目编号2012CB517500 ; 31000585 ; 81001481
资助机构National Basic Research program of China ; National Natural Science Foundation of China
引用统计
被引频次:18[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63130
专题北京大学基础医学院_北京大学系统生物医学研究所
北京大学基础医学院
作者单位1.Peking Univ, Inst Syst Biomed, Beijing 100191, Peoples R China
2.Peking Univ, MOE Kay Lab Cardiovasc Sci, Beijing 100191, Peoples R China
3.Peking Univ, Dept Biomed Informat, Beijing 100191, Peoples R China
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GB/T 7714
Chen, Geng,Wang, Juan,Cui, Qinghua. Could circulating miRNAs contribute to cancer therapy?[J]. TRENDS IN MOLECULAR MEDICINE,2013,19(2):71-73.
APA Chen, Geng,Wang, Juan,&Cui, Qinghua.(2013).Could circulating miRNAs contribute to cancer therapy?.TRENDS IN MOLECULAR MEDICINE,19(2),71-73.
MLA Chen, Geng,et al."Could circulating miRNAs contribute to cancer therapy?".TRENDS IN MOLECULAR MEDICINE 19.2(2013):71-73.
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