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学科主题口腔医学
Clinicopathological study of distant metastases of salivary adenoid cystic carcinoma
Gao, M.1; Hao, Y.2; Huang, M. X.1; Ma, D. Q.1; Luo, H. Y.3; Gao, Y.3; Peng, X.1; Yu, G. Y.1
关键词salivary adenoid cystic carcinoma distant metastasis prognosis risk factor squamous cell carcinoma
刊名INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
2013-08-01
DOI10.1016/j.ijom.2013.04.006
42期:8页:923-928
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Dentistry, Oral Surgery & Medicine ; Surgery
研究领域[WOS]Dentistry, Oral Surgery & Medicine ; Surgery
关键词[WOS]SUBMANDIBULAR-GLAND ; RISK-FACTORS ; HEAD ; NECK ; PREDICTORS ; ORIGIN
英文摘要

Most studies of the clinicopathological characteristics and prognosis of patients with distant metastasis of salivary adenoid cystic carcinoma (SACC) have used small patient samples. To further explore this issue, a descriptive and prognostic study of 467 patients with SACC who were treated from 1963 to 2009 was conducted at a single institution. One hundred and forty-five patients (31.0%) had distant metastases. At least 20% of patients who presented with the early-stage disease and no recurrence developed distant metastasis. The overall 5-, 10-, and 20- year survival rates were 85.6%, 67.4%, and 50.4%, respectively, for patients without distant metastasis, and 69.1%, 45.7%, and 14.3%, respectively, for patients with distant metastasis. The median survival time after distant metastasis was 36 months (range 1-112 months). The prognosis was similar between patients who received treatment for metastasis and those who did not. Patients who were diagnosed with early-stage disease and without local recurrence of the primary tumours could also develop distant metastases. The biological characteristics of adenoid cystic carcinoma were different from those of squamous cell carcinoma. At present, the effectiveness of treatment for distant metastases is not ideal and further research is needed.

语种英语
WOS记录号WOS:000321481800001
引用统计
被引频次:29[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63147
专题北京大学口腔医学院_第二门诊部
北京大学第一临床医学院_小儿外科
北京大学口腔医学院_外科
作者单位1.Peking Univ, Sch & Hosp Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100081, Peoples R China
2.Peking Univ, Sch & Hosp Stomatol, Dent Ctr 2, Beijing 100081, Peoples R China
3.Peking Univ, Sch & Hosp Stomatol, Dept Oral Pathol, Beijing 100081, Peoples R China
推荐引用方式
GB/T 7714
Gao, M.,Hao, Y.,Huang, M. X.,et al. Clinicopathological study of distant metastases of salivary adenoid cystic carcinoma[J]. INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY,2013,42(8):923-928.
APA Gao, M..,Hao, Y..,Huang, M. X..,Ma, D. Q..,Luo, H. Y..,...&Yu, G. Y..(2013).Clinicopathological study of distant metastases of salivary adenoid cystic carcinoma.INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY,42(8),923-928.
MLA Gao, M.,et al."Clinicopathological study of distant metastases of salivary adenoid cystic carcinoma".INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY 42.8(2013):923-928.
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