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IR@PKUHSC  > 北京大学药学院  > 化学生物学系  > 期刊论文
学科主题: 药学
题名:
Perspective on Nrf2, Epigenomics and Cancer Stem Cells in Cancer Chemoprevention Using Dietary Phytochemicals and Traditional Chinese Medicines
作者: Su, Zheng-Yuan1; Shu, Limin1; Lee, Jong Hun1; Fuentes, Francis1,2; Wang, Hu1; Wu, Tien-Yuan1; Yu, Siwang3; Kong, Ah-Ng Tony1
关键词: cancer chemoprevention ; Nrf2 ; epigenomics ; dietary components ; phytochemical ; traditional Chinese medicines
刊名: PROGRESS IN CHEMISTRY
发表日期: 2013-09-24
卷: 25, 期:9, 页:1526-1543
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
关键词[WOS]: NF-KAPPA-B ; HISTONE ACETYLTRANSFERASE ACTIVITY ; TUMOR-SUPPRESSOR GENES ; GREEN TEA POLYPHENOLS ; HUMAN PROSTATE-CANCER ; DNA METHYLTRANSFERASE INHIBITORS ; ELEMENT SIGNALING PATHWAY ; ACUTE MYELOID-LEUKEMIA ; BREAST-CANCER ; OXIDATIVE STRESS
英文摘要:

Cancer is one of the leading causes of death worldwide. The innovation of modern diagnostics and chemotherapeutics has improved cancer patients′ treatment and care, but advanced stages of cancer remain extremely challenging to treat. Therefore, new and creative approaches are needed to prevent and treat cancer. Herbal medicines have been used for many centuries to prevent diseases such as cancer. Funding agencies, such as the National Cancer Institute in the United States, have recently emphasized support for cancer chemoprevention research using natural phytochemicals and non-toxic drugs such as nonsteroidal anti-inflammatory drugs (NSAIDs) to prevent or delay the onset of cancer. This perspective distills the latest in cancer chemoprevention research using bioactive components from fruits, vegetables, green tea and Traditional Chinese Medicines (TCM), focusing on Nrf2, epigenomic and cancer stem cell effects.

语种: 英语
WOS记录号: WOS:000326412200012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63169
Appears in Collections:北京大学药学院_化学生物学系_期刊论文

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作者单位: 1.Rutgers State Univ, Ernest Mario Sch Pharm, Dept Pharmaceut, Ctr Canc Prevent Res, Piscataway, NJ 08854 USA
2.Univ Arturo Prat, Dept Agr Desierto & Biotecnol, Iquique, Chile
3.Peking Univ, Sch Pharmaceut Sci, Hlth Sci Ctr, Dept Biol Chem, Beijing 100190, Peoples R China

Recommended Citation:
Su, Zheng-Yuan,Shu, Limin,Lee, Jong Hun,et al. Perspective on Nrf2, Epigenomics and Cancer Stem Cells in Cancer Chemoprevention Using Dietary Phytochemicals and Traditional Chinese Medicines[J]. PROGRESS IN CHEMISTRY,2013,25(9):1526-1543.
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