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学科主题: 临床医学
题名:
A randomized double-blind placebo-controlled study of Pu′er tea (ae (TM)(R) ae ′+/- eOE) extract on the regulation of metabolic syndrome
作者: Chu Song-ling1; Fu Hong1; Yang Jin-xia1; Liu Geng-xin1; Dou Pan1; Zhang Liang2; Tu Peng-fei2; Wang Xue-mei1
关键词: tea ; metabolic syndrome ; randomized controlled clinical study
刊名: CHINESE JOURNAL OF INTEGRATIVE MEDICINE
发表日期: 2011-07-01
DOI: 10.1007/s11655-011-0781-4
卷: 17, 期:7, 页:492-498
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Integrative & Complementary Medicine
研究领域[WOS]: Integrative & Complementary Medicine
关键词[WOS]: INSULIN-RESISTANCE
英文摘要:

To explore the regulative efficacy of Pu′er tea (ae (TM)(R) ae ′+/- eOE ) extract on metabolic syndrome.

Ninety patients with metabolic syndrome were randomly divided into two groups, the intervention group administered with Pu′er tea extract, and the placebo group with placebo capsules. After 3 months′ treatment, body mass index, waist hip ratio, blood lipids, blood sugar, immune and inflammatory index, and oxidation index of the patients with metabolic syndrome were tested and analyzed.

In the intervention group, the body mass index, waist-hip ratio, fasting and 2 h postprandial blood glucose, serum total cholesterol, triglycerides, low density lipoprotein and apolipoprotein B-100 all decreased in the patients with metabolic syndrome, and also the high-density lipoprotein level increased and apolipoprotein A-1 showed the tendency to increase. Serum C-reactive protein, tumor necrosis factor-alpha, and interleukin-6 were decreased in the intervention group. Interleukin-10 level was increased, MDA was decreased and superoxide dismutase was increased. Compared with before treatment and the placebo group, there were significant differences (P < 0.05, P < 0.01).

Pu′er tea demonstrated excellent potential in improving central obesity, adjusting blood lipid, lowering blood sugar, regulating immunity and resisting oxidation. It can adjust the metabolic syndrome of different clinical phenotypes to different degrees, and is ideally fit for early prevention of metabolic syndrome.

语种: 英语
所属项目编号: 2007YNCXB-01-01
项目资助者: Major Project of Development of Biotic Resources in Yunnan Province
WOS记录号: WOS:000292305400002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63170
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.Beijing Med Univ, Integrat Chinese & Western Med Lab, Hosp 1, Grad Sch Integrat Chinese & Western Med, Beijing 100034, Peoples R China
2.Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China

Recommended Citation:
Chu Song-ling,Fu Hong,Yang Jin-xia,et al. A randomized double-blind placebo-controlled study of Pu&prime;er tea (ae (TM)(R) ae &prime;+/- eOE) extract on the regulation of metabolic syndrome[J]. CHINESE JOURNAL OF INTEGRATIVE MEDICINE,2011,17(7):492-498.
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