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A randomized double-blind placebo-controlled study of Pu′er tea (ae (TM)(R) ae ′+/- eOE) extract on the regulation of metabolic syndrome
Chu Song-ling1; Fu Hong1; Yang Jin-xia1; Liu Geng-xin1; Dou Pan1; Zhang Liang2; Tu Peng-fei2; Wang Xue-mei1
关键词tea metabolic syndrome randomized controlled clinical study
刊名CHINESE JOURNAL OF INTEGRATIVE MEDICINE
2011-07-01
DOI10.1007/s11655-011-0781-4
17期:7页:492-498
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Integrative & Complementary Medicine
研究领域[WOS]Integrative & Complementary Medicine
关键词[WOS]INSULIN-RESISTANCE
英文摘要

To explore the regulative efficacy of Pu′er tea (ae (TM)(R) ae ′+/- eOE ) extract on metabolic syndrome.

Ninety patients with metabolic syndrome were randomly divided into two groups, the intervention group administered with Pu′er tea extract, and the placebo group with placebo capsules. After 3 months′ treatment, body mass index, waist hip ratio, blood lipids, blood sugar, immune and inflammatory index, and oxidation index of the patients with metabolic syndrome were tested and analyzed.

In the intervention group, the body mass index, waist-hip ratio, fasting and 2 h postprandial blood glucose, serum total cholesterol, triglycerides, low density lipoprotein and apolipoprotein B-100 all decreased in the patients with metabolic syndrome, and also the high-density lipoprotein level increased and apolipoprotein A-1 showed the tendency to increase. Serum C-reactive protein, tumor necrosis factor-alpha, and interleukin-6 were decreased in the intervention group. Interleukin-10 level was increased, MDA was decreased and superoxide dismutase was increased. Compared with before treatment and the placebo group, there were significant differences (P < 0.05, P < 0.01).

Pu′er tea demonstrated excellent potential in improving central obesity, adjusting blood lipid, lowering blood sugar, regulating immunity and resisting oxidation. It can adjust the metabolic syndrome of different clinical phenotypes to different degrees, and is ideally fit for early prevention of metabolic syndrome.

语种英语
WOS记录号WOS:000292305400002
项目编号2007YNCXB-01-01
资助机构Major Project of Development of Biotic Resources in Yunnan Province
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63170
专题北京大学第一临床医学院
北京大学药学院_天然药物学系
北京大学第一临床医学院_中医中西医结合科
北京大学第三临床医学院_麻醉科
作者单位1.Beijing Med Univ, Integrat Chinese & Western Med Lab, Hosp 1, Grad Sch Integrat Chinese & Western Med, Beijing 100034, Peoples R China
2.Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Chu Song-ling,Fu Hong,Yang Jin-xia,et al. A randomized double-blind placebo-controlled study of Pu&prime;er tea (ae (TM)(R) ae &prime;+/- eOE) extract on the regulation of metabolic syndrome[J]. CHINESE JOURNAL OF INTEGRATIVE MEDICINE,2011,17(7):492-498.
APA Chu Song-ling.,Fu Hong.,Yang Jin-xia.,Liu Geng-xin.,Dou Pan.,...&Wang Xue-mei.(2011).A randomized double-blind placebo-controlled study of Pu′er tea (ae (TM)(R) ae ′+/- eOE) extract on the regulation of metabolic syndrome.CHINESE JOURNAL OF INTEGRATIVE MEDICINE,17(7),492-498.
MLA Chu Song-ling,et al."A randomized double-blind placebo-controlled study of Pu′er tea (ae (TM)(R) ae ′+/- eOE) extract on the regulation of metabolic syndrome".CHINESE JOURNAL OF INTEGRATIVE MEDICINE 17.7(2011):492-498.
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