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Total Synthesis of Dictyodendrins B and E
Liang, Jingjing1; Hu, Weimin1; Tao, Pengyu1; Jia, Yanxing1,2
刊名JOURNAL OF ORGANIC CHEMISTRY
2013-06-07
DOI10.1021/jo400841d
78期:11页:5810-5815
收录类别SCI ; IC ; CCR
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Organic
资助者National Natural Science Foundation of China ; National Basic Research Program of China (973 Program) ; Ph.D. Programs Foundation of Ministry of Education of China ; National Natural Science Foundation of China ; National Basic Research Program of China (973 Program) ; Ph.D. Programs Foundation of Ministry of Education of China
研究领域[WOS]Chemistry
关键词[WOS]C-H ACTIVATION ; INTERNAL ALKYNES ; ORGANIC-SYNTHESIS ; CASCADE REACTIONS ; NATURAL-PRODUCTS ; ATOM ECONOMY ; TELOMERASE ; INDOLES ; HETEROANNULATION ; ANNULATION
英文摘要

The concise synthesis of the novel telomerase inhibitors dictyodendrins B and E was completed in only 9 and 11 steps (longest linear sequence). The highly convergent strategy employed a palladium-catalyzed Larock indole synthesis and a palladium-mediated one-pot consecutive Buchwald-Hartwig amination/C H activation reaction as key steps. The present synthesis exhibits respectable levels of atom-, redox-, and step-economy.

语种英语
所属项目编号21290180 ; 20972007 ; 2010CB833200 ; 20120001110100
资助者National Natural Science Foundation of China ; National Basic Research Program of China (973 Program) ; Ph.D. Programs Foundation of Ministry of Education of China ; National Natural Science Foundation of China ; National Basic Research Program of China (973 Program) ; Ph.D. Programs Foundation of Ministry of Education of China
WOS记录号WOS:000320298700077
引用统计
被引频次:26[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63191
专题北京大学药学院
作者单位1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
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GB/T 7714
Liang, Jingjing,Hu, Weimin,Tao, Pengyu,et al. Total Synthesis of Dictyodendrins B and E[J]. JOURNAL OF ORGANIC CHEMISTRY,2013,78(11):5810-5815.
APA Liang, Jingjing,Hu, Weimin,Tao, Pengyu,&Jia, Yanxing.(2013).Total Synthesis of Dictyodendrins B and E.JOURNAL OF ORGANIC CHEMISTRY,78(11),5810-5815.
MLA Liang, Jingjing,et al."Total Synthesis of Dictyodendrins B and E".JOURNAL OF ORGANIC CHEMISTRY 78.11(2013):5810-5815.
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