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A Versatile Approach to N-Alkylated 1,4-Dideoxy-1,4-imino-D-arabinitols and 1,4-Dideoxy-1,4-imino-L-xylitols
Wang, Guan-Nan; Yang, Lin; Zhang, Li-He; Ye, Xin-Shan1
刊名JOURNAL OF ORGANIC CHEMISTRY
2011-04-01
DOI10.1021/jo1020322
76期:7页:2001-2009
收录类别SCI ; IC ; CCR
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Organic
研究领域[WOS]Chemistry
关键词[WOS]NATURALLY-OCCURRING IMINOSUGARS ; VIRAL DIARRHEA VIRUS ; GLYCOSIDASE INHIBITORS ; ASYMMETRIC-SYNTHESIS ; BIOLOGICAL-ACTIVITY ; NATURAL OCCURRENCE ; PYRROLIDINES ; DERIVATIVES ; AGENTS ; SUGARS
英文摘要

A versatile and concise synthesis of N-alkylated 1,4-dideoxy-1,4-imino-D-arabinitol and 1,4-dideoxy-1,4-imino-L-xylitol derivatives is described. These were prepared using pseudohemiketal lactams as key intermediates, which in turn were obtained from sucrose. The key intermediates were prepared by a diastereospecific tandem reaction which facilitated the introduction of various substituents on the nitrogen atom of the iminosugars.

语种英语
WOS记录号WOS:000288692000005
项目编号90713010 ; 2009ZX09501-011
资助机构National Natural Science Foundation of China ; Ministry of Science and Technology of China
引用统计
被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63194
专题北京大学药学院
北京大学药学院_药物化学系
作者单位1.Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Peking Univ, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Wang, Guan-Nan,Yang, Lin,Zhang, Li-He,et al. A Versatile Approach to N-Alkylated 1,4-Dideoxy-1,4-imino-D-arabinitols and 1,4-Dideoxy-1,4-imino-L-xylitols[J]. JOURNAL OF ORGANIC CHEMISTRY,2011,76(7):2001-2009.
APA Wang, Guan-Nan,Yang, Lin,Zhang, Li-He,&Ye, Xin-Shan.(2011).A Versatile Approach to N-Alkylated 1,4-Dideoxy-1,4-imino-D-arabinitols and 1,4-Dideoxy-1,4-imino-L-xylitols.JOURNAL OF ORGANIC CHEMISTRY,76(7),2001-2009.
MLA Wang, Guan-Nan,et al."A Versatile Approach to N-Alkylated 1,4-Dideoxy-1,4-imino-D-arabinitols and 1,4-Dideoxy-1,4-imino-L-xylitols".JOURNAL OF ORGANIC CHEMISTRY 76.7(2011):2001-2009.
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