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Intravitreal Bevacizumab for Ocular Metastasis of Multiple Myeloma
Zhou, Qiang1; Liang, Jianhong2; Lu, Hong1
关键词multiple myeloma ocular metastasis biopsy intravitreal injection bevacizumab
刊名OPTOMETRY AND VISION SCIENCE
2013-09-01
90期:9页:E236-E240
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Ophthalmology
研究领域[WOS]Ophthalmology
关键词[WOS]RANDOMIZED-TRIAL ; NEOVASCULAR GLAUCOMA ; PHASE-II ; CANCER ; IRIS ; REGRESSION ; CARCINOMA
英文摘要

Purpose. Multiple myeloma is the most common plasma cell tumor; however, ocular plasmacytomas are rare. Few cases of binocular metastasis have been reported. The authors review a case study using intraocular bevacizumab to treat secondary glaucoma and binocular metastasis from multiple myeloma.

Case Report. A 59-year-old woman with a 13-month history of multiple myeloma was found to have a suspected masquerade syndrome OS and subsequently developed a neovascular glaucoma within 2 months. Intravitreal bevacizumab injection OS controlled the intraocular pressure and inhibited ocular metastasis. The methods of therapy administration in this case are consistent with procedures commonly used in clinical practice when using bevacizumab to treat other etiologies, such as choroidal neovascular membranes. Lost to follow-up until 2 months later, the patient presented with ocular metastasis OD with the same changes as observed OS. Conjunctival biopsy revealed subconjunctival plasmoma OD. After intravitreal bevacizumab injection, neovascular glaucoma OD was partly controlled.

Conclusions. Secondary ocular plasmacytoma, despite its rarity, should be considered in patients with multiple myeloma. Intravitreal bevacizumab injection may be a promising treatment for ocular metastases and associated secondary or neovascular glaucoma.

语种英语
WOS记录号WOS:000330347600001
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63218
专题北京大学第二临床医学院_眼科
作者单位1.Capital Med Univ, Beijing Chaoyang Hosp, Dept Ophthalmol, Beijing 100020, Peoples R China
2.Peking Univ, Peoples Hosp, Dept Ophthalmol, Beijing 100871, Peoples R China
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Zhou, Qiang,Liang, Jianhong,Lu, Hong. Intravitreal Bevacizumab for Ocular Metastasis of Multiple Myeloma[J]. OPTOMETRY AND VISION SCIENCE,2013,90(9):E236-E240.
APA Zhou, Qiang,Liang, Jianhong,&Lu, Hong.(2013).Intravitreal Bevacizumab for Ocular Metastasis of Multiple Myeloma.OPTOMETRY AND VISION SCIENCE,90(9),E236-E240.
MLA Zhou, Qiang,et al."Intravitreal Bevacizumab for Ocular Metastasis of Multiple Myeloma".OPTOMETRY AND VISION SCIENCE 90.9(2013):E236-E240.
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