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A novel method for the synthesis of sulfur substituted-cyclopyrophosphate of cADPR analogs
Wu, Ren-Min; Qi, Na; Jia, Yu-Wen; Guan, Zhu; Zhang, Liang-Ren; Zhang, Li-He; Yang, Zhen-Jun
关键词cADPR cIDPRE Phosphoramidite strategy Cyclopyrophosphate
刊名CHINESE CHEMICAL LETTERS
2014-12-01
DOI10.1016/j.cclet.2014.07.010
25期:12页:1583-1585
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
研究领域[WOS]Chemistry
关键词[WOS]CYCLIC ADP-RIBOSE ; ADENOSINE-DIPHOSPHORIBOSE CADPR ; RELEASE ACTIVITY ; CALCIUM-RELEASE ; PHARMACOLOGY
英文摘要

A facile and efficient protocol for the synthesis of sulfur substituted-cyclopyrophosphate of cIDPRE (P-S(1)-cIDPRE) was developed. The key step was the cyclization process which was completed by the sulfur substituted cyclization precursor 1b via the one-pot phosphoramidite strategy. (C) 2014 Zhen-Jun Yang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

语种英语
所属项目编号21332010 ; 21172010 ; 21002004
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
WOS记录号WOS:000348013600017
Citation statistics
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63232
Collection北京大学药学院
作者单位Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
Recommended Citation
GB/T 7714
Wu, Ren-Min,Qi, Na,Jia, Yu-Wen,et al. A novel method for the synthesis of sulfur substituted-cyclopyrophosphate of cADPR analogs[J]. CHINESE CHEMICAL LETTERS,2014,25(12):1583-1585.
APA Wu, Ren-Min.,Qi, Na.,Jia, Yu-Wen.,Guan, Zhu.,Zhang, Liang-Ren.,...&Yang, Zhen-Jun.(2014).A novel method for the synthesis of sulfur substituted-cyclopyrophosphate of cADPR analogs.CHINESE CHEMICAL LETTERS,25(12),1583-1585.
MLA Wu, Ren-Min,et al."A novel method for the synthesis of sulfur substituted-cyclopyrophosphate of cADPR analogs".CHINESE CHEMICAL LETTERS 25.12(2014):1583-1585.
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