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学科主题: 临床医学
题名:
Comparative Cytotoxicity Study of Water-Soluble Carbon Nanoparticles on Plant Cells
作者: Dang, Song1; Liu, Qiaoling1; Zhang, Xuejie1; He, Kangmin1,2,3; Wang, Chunru1; Fang, Xiaohong1
关键词: Single-Walled Carbon Nanotubes ; Fullerenes ; Cytotoxicity ; Fluorescence Imaging ; BY-2 Cells
刊名: JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
发表日期: 2012-06-01
DOI: 10.1166/jnn.2012.6216
卷: 12, 期:6, 页:4478-4484
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
研究领域[WOS]: Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
关键词[WOS]: ACTIN CYTOSKELETON ; OXIDATIVE STRESS ; NANOTUBES ; NANOMATERIALS ; DEATH ; ARABIDOPSIS ; TOXICITY ; RICE ; FULLERENE ; GROWTH
英文摘要:

This study provides a parallel cytotoxicity study of water-soluble single-walled carbon nanotubes and fullerene C-70(C(COOH)(2))(4-8) on Nicotiana tabacum BY-2 cells. After BY-2 cells were treated with single-walled carbon nanotubes or C-70(C(COOH)(2))(4-8), the cells adopted a shrunken morphology and exhibited lower proliferation rate. Fluorescence imaging of the treated cells revealed increased reactive oxygen species generation, abnormal mitochondrial distribution, decreased mitochondrial activity, and impaired actin cytoskeleton arrangement. However, no obvious cells death was induced by either single-walled carbon nanotubes or C-70(C(COOH)(2))(4-8). Compared with single-walled carbon nanotubes, C-70(C(COOH)(2))(4-8) exerted more serious adverse effects on BY-2 cells.

语种: 英语
所属项目编号: 2011CB911001 ; 21121063
项目资助者: National Basic Research Program of China ; NSFC ; Chinese Academy of Sciences
WOS记录号: WOS:000306861000005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63235
Appears in Collections:北京大学第三临床医学院_心血管内科_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Chem, Key Lab Mol Nanostruct & Nanotechnol, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
2.Peking Univ, Inst Vasc Med, Hosp 3,Minist Educ,Key Lab Mol Cardiovasc Sci, Minist Hlth,Key Lab Cardiovasc Mol Biol & Regulat, Beijing 100191, Peoples R China
3.Peking Univ, Acad Adv Interdisciplinary Studies, Beijing 100191, Peoples R China

Recommended Citation:
Dang, Song,Liu, Qiaoling,Zhang, Xuejie,et al. Comparative Cytotoxicity Study of Water-Soluble Carbon Nanoparticles on Plant Cells[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2012,12(6):4478-4484.
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