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Levels and profiles of long-chain perfluorinated carboxylic acids in human breast milk and infant formulas in East Asia
Fujii, Yukiko1; Yan, Junxia1; Harada, Kouji H.1; Hitomi, Toshiaki1; Yang, Hyeran1; Wang, Peiyu2; Koizumi, Akio1
关键词Human breast milk Perfluorinated carboxylic acids Japan Korea China Asia
刊名CHEMOSPHERE
2012
DOI10.1016/j.chemosphere.2011.10.035
86期:3页:315-321
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Environmental Sciences
研究领域[WOS]Environmental Sciences & Ecology
关键词[WOS]PERFLUOROOCTANOIC ACID ; PERFLUOROALKYL ACIDS ; HUMAN EXPOSURE ; SERUM SAMPLES ; JAPAN ; PFOA ; SULFONATE ; PERFLUOROCARBOXYLATES ; POLLUTANTS ; LACTATION
英文摘要

In this study, 90 human breast milk samples collected from Japan, Korea, and China were analyzed for perfluorooctanoic acid (PFOA) (C8), perfluorononanoic acid (PFNA) (C9), perfluorodecanoic acid (PFDA) (C10), perfluoroundecanoic acid (PFUnDA) (C11), perfluorododecanoic acid (PFDoDA) (C12), and perfluorotridecanoic acid (PFTrDA) (03). In addition, infant formulas (n = 9) obtained from retail stores in China and Japan were analyzed. PFOA was the predominant compound and was detected in more than 60% of samples in all three countries. The PFOA, PFNA, PFDA, and PFUnDA levels in Japan were significantly higher than those in Korea and China (p < 0.05). The PFTrDA level was highest in Korea (p < 0.05). The median PFOA concentrations were 89 pg mL(-1) (48% of total perfluorinated carboxylic acids (PFCAs) (C8-C13)) in Japan, 62 pg mL(-1) (54%) in Korea, and 51 pg mL(-1) (61%) in China. The remaining Sigma PFCAs (C9-C13) were 95 pg mL(-1) in Japan, 52 pg mL(-1) in Korea, and 33 pg mL(-1) in China. Among the long-chain PFCAs, odd-numbered PFCAs were more frequently detected than even-numbered PFCAs, except for PFDA in Japan. There were no evident correlations between the mother′s demographic factors and the PFCA concentrations. PFOA, PFNA, and PFDA were frequently detected in both Japan and China, but there were no significant differences between the two countries. The total PFCA concentrations in the infant formulas were lower than those in the breast milk samples in Japan (p < 0.05), but not in China (p > 0.05). In conclusion, various PFCAs were detected in human breast milk samples from East Asian countries. (C) 2011 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000300210200016
项目编号1300001 ; H21-Food-003
资助机构Special Coordination Funds for Promoting Science and Technology ; Japan Science and Technology Agency ; Ministry of Health, Labour and Welfare of Japan
引用统计
被引频次:26[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63396
专题北京大学公共卫生学院
北京大学药学院_药剂学系
作者单位1.Kyoto Univ, Dept Hlth & Environm Sci, Grad Sch Med, Sakyo Ku, Kyoto 6068501, Japan
2.Peking Univ, Dept Social Med & Hlth Educ, Sch Publ Hlth, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Fujii, Yukiko,Yan, Junxia,Harada, Kouji H.,et al. Levels and profiles of long-chain perfluorinated carboxylic acids in human breast milk and infant formulas in East Asia[J]. CHEMOSPHERE,2012,86(3):315-321.
APA Fujii, Yukiko.,Yan, Junxia.,Harada, Kouji H..,Hitomi, Toshiaki.,Yang, Hyeran.,...&Koizumi, Akio.(2012).Levels and profiles of long-chain perfluorinated carboxylic acids in human breast milk and infant formulas in East Asia.CHEMOSPHERE,86(3),315-321.
MLA Fujii, Yukiko,et al."Levels and profiles of long-chain perfluorinated carboxylic acids in human breast milk and infant formulas in East Asia".CHEMOSPHERE 86.3(2012):315-321.
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