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学科主题基础医学
Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy
Ding, Yichen1; Zhang, Yu2; Peng, Tong1; Lu, Yiqing4; Jin, Dayong4; Ren, Qiushi1; Liu, Yuying2; Han, Jingyan2,3; Xi, Peng1
刊名SCIENTIFIC REPORTS
2013-05-03
DOI10.1038/srep01762
3
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Multidisciplinary Sciences
研究领域[WOS]Science & Technology - Other Topics
关键词[WOS]ISCHEMIA-REPERFUSION ; LEUKOCYTE ADHESION ; LACTIC-ACID ; IN-VIVO ; ISCHEMIA/REPERFUSION ; INFLAMMATION ; RESPONSES ; INJURY
英文摘要

Ischemia-reperfusion (I/R) injury model has been widely applied to the study of microcirculation disturbance. In this work, we used laser oblique scanning optical microscopy (LOSOM) to observe the microcirculation system in the mesentery of rat model. Utilizing a localized point-scanning detection scheme, high-contrast images of leukocytes were obtained. The extended detection capability facilitated both the automatic in vivo cell counting and the accurate measurement of the rolling velocity of leukocytes. Statistical analysis of the different treatment groups suggested that the distinction between I/R and sham groups with time lapse is significant.

语种英语
WOS记录号WOS:000318333900001
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63465
专题北京大学基础医学院
作者单位1.Peking Univ, Coll Engn, Dept Biomed Engn, Beijing 100871, Peoples R China
2.Peking Univ, Sch Basic Med Sci, Dept Integrat Chinese & Western Med, Beijing 100191, Peoples R China
3.Peking Univ, Hlth Sci Ctr, Tasly Microcirculat Res Ctr, Beijing 100191, Peoples R China
4.Macquarie Univ, MQphoton Res Ctr, Adv Cytometry Labs, Sydney, NSW 2109, Australia
推荐引用方式
GB/T 7714
Ding, Yichen,Zhang, Yu,Peng, Tong,et al. Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy[J]. SCIENTIFIC REPORTS,2013,3.
APA Ding, Yichen.,Zhang, Yu.,Peng, Tong.,Lu, Yiqing.,Jin, Dayong.,...&Xi, Peng.(2013).Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy.SCIENTIFIC REPORTS,3.
MLA Ding, Yichen,et al."Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy".SCIENTIFIC REPORTS 3(2013).
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