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学科主题: 临床医学
题名:
Symmetry based prostate cancer detection
作者: Yang, L.1,2; Xie, Y.1,3; Li, B.4; Xie, M.1; Wang, X.5; Zhang, J.3,4
刊名: BRITISH JOURNAL OF RADIOLOGY
发表日期: 2015
DOI: 10.1259/bjr.20150132
卷: 88, 期:1050
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: CONTRAST-ENHANCED MRI ; ADENOCARCINOMA ; CARCINOMA ; LOCALIZATION ; STATISTICS ; ANTIGEN ; IMAGES
英文摘要:

Objective: To retrospectively assess the value of left and right half symmetry analysis in prostate T-2 weighted images (T2WI) for improving prostate cancer (PCa) screening.

Methods: T2WI and other data of a total of 66 males were collected; the control group and cancer group had 33 patients each. Thresholding geometric active contours algorithm was used for prostate region segmentation, and the measure of local reflectional symmetry algorithm was applied to extract the longitudinal symmetry axes. After that, cross-correlation coefficients (CCs) of the left and right halves of each prostate were obtained.

Results: Data analysis showed that the mean and variance of the value of the left and right half CCs of prostate T2WI in the cancer group and control group were 0.73 +/- 0.05 and 0.82 +/- 0.06, respectively. The area under the receiver operating characteristic curve was 0.87, and the specificity and the sensitivity were 91% and 70%, respectively. The p < 0.001 indicated that the value of CCs of the prostates between the two groups was significantly different.

Conclusion: The symmetry in T2WI is a potential useful index for PCa screening and has a potential value for PCa detection and localizations of tumours for biopsy.

Advances in knowledge: Texture bilateral symmetry of prostate T2WI is employed to screen the suspected prostate tumour.

语种: 英语
WOS记录号: WOS:000358534600022
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63519
Appears in Collections:北京大学第一临床医学院_放射治疗科_期刊论文

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作者单位: 1.Peking Univ, Coll Engn, Beijing 100871, Peoples R China
2.Chengdu Univ Informat Technol, Coll Elect Engn, Chengdu, Sichuan, Peoples R China
3.Univ Elect Sci & Technol China, Sch Elect Engn, Chengdu 610054, Sichuan, Peoples R China
4.Peking Univ, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China
5.Peking Univ, Hosp 1, Dept Radiol, Beijing 100871, Peoples R China

Recommended Citation:
Yang, L.,Xie, Y.,Li, B.,et al. Symmetry based prostate cancer detection[J]. BRITISH JOURNAL OF RADIOLOGY,2015,88(1050).
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