IR@PKUHSC  > 北京大学第一临床医学院  > 放射治疗科
学科主题临床医学
Symmetry based prostate cancer detection
Yang, L.1,2; Xie, Y.1,3; Li, B.4; Xie, M.1; Wang, X.5; Zhang, J.3,4
刊名BRITISH JOURNAL OF RADIOLOGY
2015
DOI10.1259/bjr.20150132
88期:1050
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]CONTRAST-ENHANCED MRI ; ADENOCARCINOMA ; CARCINOMA ; LOCALIZATION ; STATISTICS ; ANTIGEN ; IMAGES
英文摘要

Objective: To retrospectively assess the value of left and right half symmetry analysis in prostate T-2 weighted images (T2WI) for improving prostate cancer (PCa) screening.

Methods: T2WI and other data of a total of 66 males were collected; the control group and cancer group had 33 patients each. Thresholding geometric active contours algorithm was used for prostate region segmentation, and the measure of local reflectional symmetry algorithm was applied to extract the longitudinal symmetry axes. After that, cross-correlation coefficients (CCs) of the left and right halves of each prostate were obtained.

Results: Data analysis showed that the mean and variance of the value of the left and right half CCs of prostate T2WI in the cancer group and control group were 0.73 +/- 0.05 and 0.82 +/- 0.06, respectively. The area under the receiver operating characteristic curve was 0.87, and the specificity and the sensitivity were 91% and 70%, respectively. The p < 0.001 indicated that the value of CCs of the prostates between the two groups was significantly different.

Conclusion: The symmetry in T2WI is a potential useful index for PCa screening and has a potential value for PCa detection and localizations of tumours for biopsy.

Advances in knowledge: Texture bilateral symmetry of prostate T2WI is employed to screen the suspected prostate tumour.

语种英语
WOS记录号WOS:000358534600022
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63519
专题北京大学第一临床医学院_放射治疗科
作者单位1.Peking Univ, Coll Engn, Beijing 100871, Peoples R China
2.Chengdu Univ Informat Technol, Coll Elect Engn, Chengdu, Sichuan, Peoples R China
3.Univ Elect Sci & Technol China, Sch Elect Engn, Chengdu 610054, Sichuan, Peoples R China
4.Peking Univ, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China
5.Peking Univ, Hosp 1, Dept Radiol, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Yang, L.,Xie, Y.,Li, B.,et al. Symmetry based prostate cancer detection[J]. BRITISH JOURNAL OF RADIOLOGY,2015,88(1050).
APA Yang, L.,Xie, Y.,Li, B.,Xie, M.,Wang, X.,&Zhang, J..(2015).Symmetry based prostate cancer detection.BRITISH JOURNAL OF RADIOLOGY,88(1050).
MLA Yang, L.,et al."Symmetry based prostate cancer detection".BRITISH JOURNAL OF RADIOLOGY 88.1050(2015).
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