|Symmetry based prostate cancer detection|
|Yang, L.1,2; Xie, Y.1,3; Li, B.4; Xie, M.1; Wang, X.5; Zhang, J.3,4|
|刊名||BRITISH JOURNAL OF RADIOLOGY|
|WOS标题词||Science & Technology|
|类目[WOS]||Radiology, Nuclear Medicine & Medical Imaging|
|研究领域[WOS]||Radiology, Nuclear Medicine & Medical Imaging|
|关键词[WOS]||CONTRAST-ENHANCED MRI ; ADENOCARCINOMA ; CARCINOMA ; LOCALIZATION ; STATISTICS ; ANTIGEN ; IMAGES|
Objective: To retrospectively assess the value of left and right half symmetry analysis in prostate T-2 weighted images (T2WI) for improving prostate cancer (PCa) screening.
Methods: T2WI and other data of a total of 66 males were collected; the control group and cancer group had 33 patients each. Thresholding geometric active contours algorithm was used for prostate region segmentation, and the measure of local reflectional symmetry algorithm was applied to extract the longitudinal symmetry axes. After that, cross-correlation coefficients (CCs) of the left and right halves of each prostate were obtained.
Results: Data analysis showed that the mean and variance of the value of the left and right half CCs of prostate T2WI in the cancer group and control group were 0.73 +/- 0.05 and 0.82 +/- 0.06, respectively. The area under the receiver operating characteristic curve was 0.87, and the specificity and the sensitivity were 91% and 70%, respectively. The p < 0.001 indicated that the value of CCs of the prostates between the two groups was significantly different.
Conclusion: The symmetry in T2WI is a potential useful index for PCa screening and has a potential value for PCa detection and localizations of tumours for biopsy.
Advances in knowledge: Texture bilateral symmetry of prostate T2WI is employed to screen the suspected prostate tumour.
|作者单位||1.Peking Univ, Coll Engn, Beijing 100871, Peoples R China|
2.Chengdu Univ Informat Technol, Coll Elect Engn, Chengdu, Sichuan, Peoples R China
3.Univ Elect Sci & Technol China, Sch Elect Engn, Chengdu 610054, Sichuan, Peoples R China
4.Peking Univ, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China
5.Peking Univ, Hosp 1, Dept Radiol, Beijing 100871, Peoples R China
|Yang, L.,Xie, Y.,Li, B.,et al. Symmetry based prostate cancer detection[J]. BRITISH JOURNAL OF RADIOLOGY,2015,88(1050).|
|APA||Yang, L.,Xie, Y.,Li, B.,Xie, M.,Wang, X.,&Zhang, J..(2015).Symmetry based prostate cancer detection.BRITISH JOURNAL OF RADIOLOGY,88(1050).|
|MLA||Yang, L.,et al."Symmetry based prostate cancer detection".BRITISH JOURNAL OF RADIOLOGY 88.1050(2015).|