|Obstetric outcome of women with uterine anomalies in China|
|Zhang Yan; Zhao Yang-yu; Qiao Jie|
|关键词||abnotmatities uterus pregnancy|
|刊名||CHINESE MEDICAL JOURNAL|
|WOS标题词||Science & Technology|
|类目[WOS]||Medicine, General & Internal|
|研究领域[WOS]||General & Internal Medicine|
|关键词[WOS]||MULLERIAN ANOMALIES ; REPRODUCTIVE-PERFORMANCE ; PREGNANCY ; MALFORMATIONS ; BIRTH|
Background Congenital uterine anomalies are associated with the highest incidence of reproductive failure and obstetric complications This study aimed to summarize the clinical characteristics and prenatal outcome of pregnancy in women with congenital uterine malformations.
Methods This retrospective study evaluated the fertility and obstetric outcome of 116 inpatients with uterine malformations with pregnancy in Peking University Third Hospital from June 1998 to June 2009. A total of 270 randomly selected pregnant women with a previously confirmed normally shaped uterus as a control group Student′s t test and analysis of variance (ANOVA) were used to compare means for normally distributed variables. The analysis was carried out using the SPSS
Results Among 21 961 deliveries in Peking University Third Hospital, 116 (0 45%) were in women with uterine anomalies. A septate uterus was present in 43 (37 1%) and the uterus didelphys in 28 (24.2%) of the 116 women identified Bicornuate uterus, arcuate and unicomate uterus were observed in 12 (10 3%), 18 (15 5%) and 15 (12 9%) patients, respectively Patients with uterine anomalies had significantly higher rates of malpresentation (38 8%), preterm delivery (19.8%), and cesarean section (78.5%) compared with the group of women with a normal uterus Patients with uterine anomalies had significantly lower mean birth-weight neonates and a significantly higher incidence of small for gestationalage (SGA) neonates, women with uterus didelphys more frequently required infertility treatment than patients with other uterine anomalies (P <0 001) The rate of malpresentation was significantly higher in patients with septated uterus in comparison with patients with uterus unicorns (P <0.05).
Conclusions Women with congenital uterinemal formation usually have higher incidence of complications during pregnancy and delivery. A septate uterus appears to be associated with poorer obstetric outcomes. Chin Med J 2010,123(4) 418-422
|作者单位||Peking Univ, Hosp 3, Dept Obstet & Gynaecol, Beijing 100083, Peoples R China|
|Zhang Yan,Zhao Yang-yu,Qiao Jie. Obstetric outcome of women with uterine anomalies in China[J]. CHINESE MEDICAL JOURNAL,2010,123(4):418-422.|
|APA||Zhang Yan,Zhao Yang-yu,&Qiao Jie.(2010).Obstetric outcome of women with uterine anomalies in China.CHINESE MEDICAL JOURNAL,123(4),418-422.|
|MLA||Zhang Yan,et al."Obstetric outcome of women with uterine anomalies in China".CHINESE MEDICAL JOURNAL 123.4(2010):418-422.|