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Studies on the large scale synthesis and anti-tumor activity of YSL
Wang, C; Ding, WF; Zhao, M; Lin, G; Peng, SQ
关键词YSL synthesis anti-tumor activity large scale
刊名PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
2003
DOI10.1081/PB-120022987
33期:3页:189-195
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemical Research Methods ; Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology
研究领域[WOS]Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology
关键词[WOS]PEPTIDE
英文摘要

H-Tyr-Ser-Leu-OH (YSL), isolated from the degradation products of porcine spleen, was synthesized by a solution method on a large scale via two synthetic strategies. Its structure was confirmed by spectroscopic and related analyses. The in vivo anti-tumor activity was evaluated with murine H22 tumor models. The result indicated that, with the administration of YSL, the survival time of the murine H22 implanted mice was significantly prolonged.

语种英语
WOS记录号WOS:000184533200003
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63562
专题北京大学药学院
作者单位Peking Univ, Coll Pharmaceut Sci, Beijing 100083, Peoples R China
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GB/T 7714
Wang, C,Ding, WF,Zhao, M,et al. Studies on the large scale synthesis and anti-tumor activity of YSL[J]. PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY,2003,33(3):189-195.
APA Wang, C,Ding, WF,Zhao, M,Lin, G,&Peng, SQ.(2003).Studies on the large scale synthesis and anti-tumor activity of YSL.PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY,33(3),189-195.
MLA Wang, C,et al."Studies on the large scale synthesis and anti-tumor activity of YSL".PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY 33.3(2003):189-195.
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