IR@PKUHSC  > 北京大学药学院
学科主题药学
Synthesis and analgesic activity of N-(N-acetyl-L-amino-acyl)-5-methoxytryptamines
Han, DM; Wang, C; Zhao, M; Peng, SQ
刊名PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
2000
30期:1页:39-47
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemical Research Methods ; Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology
研究领域[WOS]Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology
关键词[WOS]MELATONIN
英文摘要

5-Methoxytryptamine was acylated with N-acetyl-L-amino acids to give rise the corresponding N-(N-acetyl-L-amino acyl)-5-methoxytryptamines. The analgesic activity was evaluated by the tail flick test. Among the 6 compounds, the analgesic potency of N-(N-acetyl-tryptophanyl)-5-methoxytryptamine (5e) and N-(N-acetyl-glycyl)-5-methoxytryptamine (5a) are much more potent than that of melatonin.

语种英语
WOS记录号WOS:000085783700005
Citation statistics
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63647
Collection北京大学药学院
作者单位Beijing Med Univ, Coll Pharmaceut Sci, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Han, DM,Wang, C,Zhao, M,et al. Synthesis and analgesic activity of N-(N-acetyl-L-amino-acyl)-5-methoxytryptamines[J]. PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY,2000,30(1):39-47.
APA Han, DM,Wang, C,Zhao, M,&Peng, SQ.(2000).Synthesis and analgesic activity of N-(N-acetyl-L-amino-acyl)-5-methoxytryptamines.PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY,30(1),39-47.
MLA Han, DM,et al."Synthesis and analgesic activity of N-(N-acetyl-L-amino-acyl)-5-methoxytryptamines".PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY 30.1(2000):39-47.
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