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学科主题临床医学
Clinical Value of Real Time Elastography in Patients with Unexplained Cervical Lymphadenopathy: Quantitative Evaluation
Fu, Ying1; Shi, Yun-Fei2; Yan, Kun1; Wang, Yan-Jie1; Yang, Wei1; Feng, Guo-Shuang3
关键词Ultrasonography elastography cervical differential diagnosis lymphadenopathy
刊名ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
2014
DOI10.7314/APJCP.2014.15.13.5487
15期:13页:5487-5492
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology
资助者Capital Medical Development Program ; Beijing Municipal Health System Special funds of High-Level Medical Personnel Construction ; Capital Medical Development Program ; Beijing Municipal Health System Special funds of High-Level Medical Personnel Construction
研究领域[WOS]Oncology
关键词[WOS]ULTRASOUND ELASTOGRAPHY ; LYMPH-NODES ; SONOGRAPHY ; DIFFERENTIATION ; METASTASIS ; DIAGNOSIS ; CANCER ; BENIGN ; US
英文摘要

Ultrasonography is non-invasive and can give useful clues in the diagnosis of cervical lymphadenopathy, However, differential diagnosis is difficult in some situations even combined with color Doppler imaging. The present study was conducted to evaluate the clinical value of real time elastography in patients with unexplained cervical lymphadenopathy using a quantitative method. From May 2011 to February 2012, 39 enlarged lymph nodes from 39 patients with unexplained cervical lymphadenopathy were assessed. All the patients were examined by both B-mode ultrasound, color Doppler flow imaging and elastography. The method of analyzing elasto-graphic data was the calculation of the 10 parametres ("mean", "sd", "area %", "com", "kur", "ske", "con", "ent", "idm", "asm") offered by the software integrated into the Hitachi system. The findings were then correlated with the definitive tissue diagnosis obtained by lymph node dissection or biopsy. Final histology revealed 10 cases of metastatic lymph nodes, 11 cases of lymphoma, 12 cases of tuberculosis and 6 cases of nonspecific lymphadenitis. The significant distinguishing features for conventional ultrasound were the maximum short diameter (p=0.007) and absent of echogenic hilum (p=0.0293). The diagnostic accuracy was 43.6% (17/39 cases) and there were 17 patients with equivocal diagnosis. For elastography, "mean" (p=0.003), "area %" (p=0.009), "kurt" (p=0.0291), "skew" (p=0.014) and "cont" (p=0.012) demonstrated significant differences between groups. With 9 of the 17 patients with previous equivocal diagnoses (52.9%) definite and correct diagnoses could be obtained. The diagnostic accuracy for conventional ultrasound combined elastography was 69.2% (27/39 cases). There were differences in the diagnostic sensitivity of the two methods (p=0.0224). Ultrasound combined with elastography demonstrated higher rates of conclusive and accurate diagnoses in patients with unexplained cervical lymphadenopathy than conventional ultrasound. The quantitative program showed good correlation with the pathology of different lymph node diseases.

语种英语
所属项目编号2011-2015-01 ; 2013-3-086
资助者Capital Medical Development Program ; Beijing Municipal Health System Special funds of High-Level Medical Personnel Construction ; Capital Medical Development Program ; Beijing Municipal Health System Special funds of High-Level Medical Personnel Construction
WOS记录号WOS:000343722900066
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63653
专题北京大学临床肿瘤学院_超声科
作者单位1.Peking Univ, Canc Hosp & Inst, Dept Ultrasound, Beijing 100871, Peoples R China
2.Peking Univ, Canc Hosp & Inst, Dept Pathol, Key Lab Carcinogenesis & Translat Res,Minist Educ, Beijing 100871, Peoples R China
3.Chinese Ctr Dis Control & Prevent, Natl Ctr Publ Hlth Surveillance & Informat Serv, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Fu, Ying,Shi, Yun-Fei,Yan, Kun,et al. Clinical Value of Real Time Elastography in Patients with Unexplained Cervical Lymphadenopathy: Quantitative Evaluation[J]. ASIAN PACIFIC JOURNAL OF CANCER PREVENTION,2014,15(13):5487-5492.
APA Fu, Ying,Shi, Yun-Fei,Yan, Kun,Wang, Yan-Jie,Yang, Wei,&Feng, Guo-Shuang.(2014).Clinical Value of Real Time Elastography in Patients with Unexplained Cervical Lymphadenopathy: Quantitative Evaluation.ASIAN PACIFIC JOURNAL OF CANCER PREVENTION,15(13),5487-5492.
MLA Fu, Ying,et al."Clinical Value of Real Time Elastography in Patients with Unexplained Cervical Lymphadenopathy: Quantitative Evaluation".ASIAN PACIFIC JOURNAL OF CANCER PREVENTION 15.13(2014):5487-5492.
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