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学科主题: 口腔医学
题名:
Clinical Study of Sclerotherapy of Maxillofacial Venous Malformation Using Absolute Ethanol and Pingyangmycin
作者: Liu, Yu1; Liu, Denggao2; Wang, Yixiang1; Zhang, Wei1; Zhao, Fuyun1
刊名: JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
发表日期: 2009
DOI: 10.1016/j.joms.2008.06.053
卷: 67, 期:1, 页:98-104
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Dentistry, Oral Surgery & Medicine
研究领域[WOS]: Dentistry, Oral Surgery & Medicine
关键词[WOS]: VASCULAR MALFORMATIONS ; HEMANGIOMAS ; NECK ; CLASSIFICATION ; CHILDHOOD ; INFANCY ; HEAD
英文摘要:

Purpose: The purpose of this study was to evaluate the outcomes of sclerotherapy of maxillofacial venous malformations by use of absolute ethanol and pingyangmycin (bleomycin A(5) hydrochloride).

Patients and Methods: We treated 23 consecutive patients with maxillofacial venous malformations by sclerotherapy with a combination of absolute ethanol and pingyangmycin under local anesthesia. The size of the lesions ranged from 2 cm x 2 cm to 12 cm x 10 cm. Venography showed the presence of large venous lakes. Venograms were obtained during the first procedure before and after injection of absolute ethanol (0-5-2.5 mL) to confirm the site of the nidus and assess the effect of sclerosis of the nidus and draining veins. Subsequently, 8 to 16 mg of pingyangmycin dissolved in 40 mL of saline solution was infused into the nidus by a dynamic infusion pump at a rate of 1 mL/min. If necessary, this procedure was repeated once in 2 or 4 weeks. The clinical outcomes and complications were evaluated.

Results: The duration of follow-up ranged from 6 to 37 months, with a mean of 20.3 months. Only 1 procedure was required in 3 patients, and the procedure was required to be repeated twice in 9 patients, 3 times in 7, and 4 times in 4. All the patients were satisfied with the treatment results, and excellent clinical results were obtained in 9 patients. There was no skin necrosis or nerve damage.

Conclusions: Percutaneous sclerotherapy with the combined use of absolute ethanol and pingyangmycin is a safe and effective treatment for maxillofacial venous malformations. (c) 2009 American Association of Oral and Maxillofacial Surgeons

语种: 英语
WOS记录号: WOS:000261981700015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63684
Appears in Collections:北京大学口腔医学院_期刊论文

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作者单位: 1.Peking Univ, Sch Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100081, Peoples R China
2.Peking Univ, Sch Stomatol, Dept Oral Radiol, Beijing 100081, Peoples R China

Recommended Citation:
Liu, Yu,Liu, Denggao,Wang, Yixiang,et al. Clinical Study of Sclerotherapy of Maxillofacial Venous Malformation Using Absolute Ethanol and Pingyangmycin[J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY,2009,67(1):98-104.
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