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Clinical Study of Sclerotherapy of Maxillofacial Venous Malformation Using Absolute Ethanol and Pingyangmycin
Liu, Yu1; Liu, Denggao2; Wang, Yixiang1; Zhang, Wei1; Zhao, Fuyun1
刊名JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
2009
DOI10.1016/j.joms.2008.06.053
67期:1页:98-104
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Dentistry, Oral Surgery & Medicine
研究领域[WOS]Dentistry, Oral Surgery & Medicine
关键词[WOS]VASCULAR MALFORMATIONS ; HEMANGIOMAS ; NECK ; CLASSIFICATION ; CHILDHOOD ; INFANCY ; HEAD
英文摘要

Purpose: The purpose of this study was to evaluate the outcomes of sclerotherapy of maxillofacial venous malformations by use of absolute ethanol and pingyangmycin (bleomycin A(5) hydrochloride).

Patients and Methods: We treated 23 consecutive patients with maxillofacial venous malformations by sclerotherapy with a combination of absolute ethanol and pingyangmycin under local anesthesia. The size of the lesions ranged from 2 cm x 2 cm to 12 cm x 10 cm. Venography showed the presence of large venous lakes. Venograms were obtained during the first procedure before and after injection of absolute ethanol (0-5-2.5 mL) to confirm the site of the nidus and assess the effect of sclerosis of the nidus and draining veins. Subsequently, 8 to 16 mg of pingyangmycin dissolved in 40 mL of saline solution was infused into the nidus by a dynamic infusion pump at a rate of 1 mL/min. If necessary, this procedure was repeated once in 2 or 4 weeks. The clinical outcomes and complications were evaluated.

Results: The duration of follow-up ranged from 6 to 37 months, with a mean of 20.3 months. Only 1 procedure was required in 3 patients, and the procedure was required to be repeated twice in 9 patients, 3 times in 7, and 4 times in 4. All the patients were satisfied with the treatment results, and excellent clinical results were obtained in 9 patients. There was no skin necrosis or nerve damage.

Conclusions: Percutaneous sclerotherapy with the combined use of absolute ethanol and pingyangmycin is a safe and effective treatment for maxillofacial venous malformations. (c) 2009 American Association of Oral and Maxillofacial Surgeons

语种英语
WOS记录号WOS:000261981700015
引用统计
被引频次:23[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63684
专题北京大学口腔医学院
北京大学口腔医学院_口腔放射科
北京大学口腔医学院_中心实验室
作者单位1.Peking Univ, Sch Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100081, Peoples R China
2.Peking Univ, Sch Stomatol, Dept Oral Radiol, Beijing 100081, Peoples R China
推荐引用方式
GB/T 7714
Liu, Yu,Liu, Denggao,Wang, Yixiang,et al. Clinical Study of Sclerotherapy of Maxillofacial Venous Malformation Using Absolute Ethanol and Pingyangmycin[J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY,2009,67(1):98-104.
APA Liu, Yu,Liu, Denggao,Wang, Yixiang,Zhang, Wei,&Zhao, Fuyun.(2009).Clinical Study of Sclerotherapy of Maxillofacial Venous Malformation Using Absolute Ethanol and Pingyangmycin.JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY,67(1),98-104.
MLA Liu, Yu,et al."Clinical Study of Sclerotherapy of Maxillofacial Venous Malformation Using Absolute Ethanol and Pingyangmycin".JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY 67.1(2009):98-104.
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