|Prevalence of Cardiovascular Disease and Risk Factors in the Chinese Population with Impaired Glucose Regulation: the 2007-2008 China National Diabetes and Metabolic Disorders Study|
|Yang, Z.1; Xing, X.1; Xiao, J.1; Lu, J.2; Weng, J.3; Jia, W.4; Ji, L.5; Shan, Z.6; Liu, J.7; Tian, H.8; Ji, Q.9; Zhu, D.10; Ge, J.11; Lin, L.12; Chen, L.13; Guo, X.14; Zhao, Z.15; Li, Q.16; Zhou, Z.17; Shan, G.18; Yang, W.1; China Natl Diabet Metab Disorders|
|关键词||diabetes cardiovascular risk management metabolic features|
|刊名||EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES|
|WOS标题词||Science & Technology|
|类目[WOS]||Endocrinology & Metabolism|
|研究领域[WOS]||Endocrinology & Metabolism|
Aims: Cardiovascular disease (CVD) is one of the most common chronic diseases in China. This aim of this study is to determine the prevalence of CVDs and risk factors in Chinese impaired glucose regulation subjects.
Methods: We used a multistage, stratified sampling method to select subjects from the general Chinese population aged 20 years and older. Subjects underwent an oral glucose tolerance test to identify normal glucose tolerance (NGT) and impaired glucose regulation including isolated impaired fasting glucose (i-IFG), impaired glucose tolerance (i-IGT), and combined IFG/IGT and diabetic mellitus (DM). A logistic regression analysis was performed to examine the association between glucose abnormalities and CVD events.
Results: We identified that 34 293 subjects had NGT, 1 469 i-IFG, 4 571 i-IGT, 957 IFG/IGT and 4 949 DM. The age-sex standardized prevalence rate of cardiovascular disease was 1.06% (95% CI 0.87-1.28), 1.79% (95% CI 1.37-2.33) and 3.83% (95% CI 2.79-5.24) in NGT, impaired glucose regulation and DM, respectively. Among impaired glucose subjects, prevalence of defined CVD risk factors (smoking, overweight, obesity, hypertension and dyslipidemia) was 29.52% (95% CI: 27.8-31.21), 36.25% (95% CI: 34.29-38.26), 10.05% (95% CI: 8.86-11.37), 36.43% (95% CI: 34.53-38.36) and 69.96% (95% CI: 67.87-71.98), respectively. Compared to 1 risk factor, the odds ratios (ORs) of CVDs with 2, 3 or 4 risk factors were 1.94 (95% CI: 0.74-5.09), 2.76 (95% CI: 1.06-7.21) and 5.84 (95% CI: 1.68-20.26), respectively. Additionally, compared to i-IFGs, ORs of CVDs with i-IGT and IFG/IGT were 2.88 (95% CI 1.36-6.01) and 2.12 (95% CI 0.83-5.44), respectively.
Conclusion: The prevalence of cardiovascular risk factors was high in the Chinese impaired glucose regulation population. The postprandial hyperglycemia is more associated with CVD than isolated fasting hyperglycemia.
|作者单位||1.Peking Univ, Hosp 1, Beijing 100871, Peoples R China|
2.Henan Prov Peoples Hosp, Zhengzhou, Henan, Peoples R China
3.Xiangya Second Hosp, Changsha, Hunan, Peoples R China
4.Peking Univ, Peoples Hosp, Beijing 100871, Peoples R China
5.Shanxi Prov Peoples Hosp, Taiyuan, Shanxi, Peoples R China
6.Xinjiang Uygur Autonomous Reg Hosp, Urumqi, Xinjiang, Peoples R China
7.China Japan Friendship Hosp, Beijing 100029, Peoples R China
8.Chinese Peoples Liberat Army Gen Hosp, Beijing, Peoples R China
9.Sun Yat Sen Univ, Hosp 3, Guangzhou 510275, Guangdong, Peoples R China
10.Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Shanghai 200030, Peoples R China
11.Chinese Med Univ, Affiliated Hosp 1, Liaoling, Peoples R China
12.Sichuan Univ, West China Hosp, Chengdu 610064, Sichuan, Peoples R China
13.Fourth Mil Med Univ, Xijing Hosp, Xian 710032, Shanxi, Peoples R China
14.Fujian Prov Hosp, Fuzhou, Fujiang, Peoples R China
15.Nanjing Univ, Sch Med, Affiliated Drum Tower Hosp, Nanjing 210008, Jiangsu, Peoples R China
16.Shandong Univ, Qilu Hosp, Jinan 250100, Shandong, Peoples R China
17.Harbin Med Univ, Affiliated Hosp 2, Harbin, Heilongjiang, Peoples R China
18.Peking Union Med Coll, Beijing 100021, Peoples R China
|Yang, Z.,Xing, X.,Xiao, J.,et al. Prevalence of Cardiovascular Disease and Risk Factors in the Chinese Population with Impaired Glucose Regulation: the 2007-2008 China National Diabetes and Metabolic Disorders Study[J]. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES,2013,121(6):372-374.|
|APA||Yang, Z..,Xing, X..,Xiao, J..,Lu, J..,Weng, J..,...&China Natl Diabet Metab Disorders.(2013).Prevalence of Cardiovascular Disease and Risk Factors in the Chinese Population with Impaired Glucose Regulation: the 2007-2008 China National Diabetes and Metabolic Disorders Study.EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES,121(6),372-374.|
|MLA||Yang, Z.,et al."Prevalence of Cardiovascular Disease and Risk Factors in the Chinese Population with Impaired Glucose Regulation: the 2007-2008 China National Diabetes and Metabolic Disorders Study".EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES 121.6(2013):372-374.|