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学科主题药学
Synthesis and potential antimetastatic activity of nionovalent and divalent beta-D-galactopyranosyl-(l -> 4)-2-acetamido-2-deoxy-D-glucopyranosides
Li, Q; Su, B; Li, H; Meng, XB; Cai, MS; Li, ZJ; Zhou, RL; Suo, TL
关键词N-acetyllactosamine monovalent divalent synthesis metastasis
刊名CARBOHYDRATE RESEARCH
2003-01-31
338期:3页:207-217
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Organic
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]ANTIGENIC DETERMINANT ; CARBOHYDRATE MOIETY ; CHEMICAL SYNTHESIS ; HEPTA-SACCHARIDE ; COMPLEX-TYPE ; PART ; GLYCOPROTEINS
英文摘要

Anomers of monovalent and divalent beta-D-galactopyranosyl-(1-->4)-2-acetamido-2-deoxy-D-gluco-pyranosides were synthesized under different glycosylation conditions, and evaluated for in vitro antimetastatic activity. Three compounds showed promising inhibitory effects on cancer cell attachment, spreading, migration, and invasion. (C) 2002 Elsevier Science Ltd. All rights reserved.

语种英语
WOS记录号WOS:000180869200001
Citation statistics
Cited Times:5[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63779
Collection北京大学药学院_化学生物学系
作者单位1.Beijing Univ, Sch Pharmaceut Sci, Dept Biol Chem, Beijing 100083, Peoples R China
2.Beijing Univ, Sch Basic Med Sci, Dept Cell Biol, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Li, Q,Su, B,Li, H,et al. Synthesis and potential antimetastatic activity of nionovalent and divalent beta-D-galactopyranosyl-(l -> 4)-2-acetamido-2-deoxy-D-glucopyranosides[J]. CARBOHYDRATE RESEARCH,2003,338(3):207-217.
APA Li, Q.,Su, B.,Li, H.,Meng, XB.,Cai, MS.,...&Suo, TL.(2003).Synthesis and potential antimetastatic activity of nionovalent and divalent beta-D-galactopyranosyl-(l -> 4)-2-acetamido-2-deoxy-D-glucopyranosides.CARBOHYDRATE RESEARCH,338(3),207-217.
MLA Li, Q,et al."Synthesis and potential antimetastatic activity of nionovalent and divalent beta-D-galactopyranosyl-(l -> 4)-2-acetamido-2-deoxy-D-glucopyranosides".CARBOHYDRATE RESEARCH 338.3(2003):207-217.
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