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学科主题: 临床医学
题名:
Evaluation of EZSCAN as a screening tool for impaired glucose metabolism
作者: Chen, Lizhu1; Chen, Xiaolu2; Ding, Rongjing3; Shi, Qiuting, Jr.4; Hu, Dayi1
关键词: Impaired glucose metabolism ; EZSCAN ; Receiver operating characteristic curve
刊名: DIABETES RESEARCH AND CLINICAL PRACTICE
发表日期: 2013-05-01
DOI: 10.1016/j.diabres.2013.03.001
卷: 100, 期:2, 页:210-214
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Endocrinology & Metabolism
研究领域[WOS]: Endocrinology & Metabolism
关键词[WOS]: LIFE-STYLE INTERVENTION ; DIABETES-MELLITUS ; PREVENTION ; DIAGNOSIS ; TOLERANCE ; NEUROPATHY ; REDUCTION ; RISK
英文摘要:

Aims: To evaluate the performance of EZSCAN as a screening tool for impaired glucose metabolism (IGM), including impaired glucose tolerance, impaired fasting glucose and undiagnosed diabetes in a Chinese population.

Methods: 876 subjects participated in the study. All subjects underwent tests of EZSCAN, glycated hemoglobin, fasting plasma glucose (FPG), and oral glucose tolerance test (OGTT). Correlation of electrical skin conductance (ESC) with glucose level was evaluated by Pearson correlation coefficient. EZSCAN performance was assessed by receiver operating characteristic curve.

Results: Among the 876 subjects, 53% had normal glucose tolerance (NGT), and 47% had IGM. The ESC for the hands and feet was 72 +/- 10 mu S and 75 +/- 7 mu S, respectively, in NGT group; and 64 +/- 13 mu S and 67 +/- 11 mu S, respectively, in IGM group. The ESC at hands and feet was significantly correlated with both 2h-OGTT and FPG (p < 0.001). NGT group demonstrated a EZSCAN score of 33 +/- 11%, which is significantly lower than that of IGM group (44 +/- 12%, p < 0.001). The cut-off point of EZSCAN for IGM detection was 40% with a sensitivity of 80% and a specificity of 72%.

Conclusions: EZSCAN is a useful screening tool for identifying subjects at increased risk for impaired glucose metabolism in prediabetes and diabetes. Diagnostic laboratory test should be performed in subjects with EZSCAN scores greater than 40%. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

语种: 英语
WOS记录号: WOS:000320590900017
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63794
Appears in Collections:北京大学第二临床医学院_心血管内科_期刊论文

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作者单位: 1.Chongqing Med Univ, Dept Cardiol, Affiliated Hosp 1, Chongqing 400016, Peoples R China
2.Chongqing Med Univ, Chongqing 400016, Peoples R China
3.Peking Univ, Dept Cardiol, Peoples Hosp, Beijing 100044, Peoples R China
4.Xianghe Chinese Med Hosp, Dept Internal Med, Xianghe 065400, Hebei Province, Peoples R China

Recommended Citation:
Chen, Lizhu,Chen, Xiaolu,Ding, Rongjing,et al. Evaluation of EZSCAN as a screening tool for impaired glucose metabolism[J]. DIABETES RESEARCH AND CLINICAL PRACTICE,2013,100(2):210-214.
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