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Evaluation of EZSCAN as a screening tool for impaired glucose metabolism
Chen, Lizhu1; Chen, Xiaolu2; Ding, Rongjing3; Shi, Qiuting, Jr.4; Hu, Dayi1
关键词Impaired glucose metabolism EZSCAN Receiver operating characteristic curve
刊名DIABETES RESEARCH AND CLINICAL PRACTICE
2013-05-01
DOI10.1016/j.diabres.2013.03.001
100期:2页:210-214
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Endocrinology & Metabolism
研究领域[WOS]Endocrinology & Metabolism
关键词[WOS]LIFE-STYLE INTERVENTION ; DIABETES-MELLITUS ; PREVENTION ; DIAGNOSIS ; TOLERANCE ; NEUROPATHY ; REDUCTION ; RISK
英文摘要

Aims: To evaluate the performance of EZSCAN as a screening tool for impaired glucose metabolism (IGM), including impaired glucose tolerance, impaired fasting glucose and undiagnosed diabetes in a Chinese population.

Methods: 876 subjects participated in the study. All subjects underwent tests of EZSCAN, glycated hemoglobin, fasting plasma glucose (FPG), and oral glucose tolerance test (OGTT). Correlation of electrical skin conductance (ESC) with glucose level was evaluated by Pearson correlation coefficient. EZSCAN performance was assessed by receiver operating characteristic curve.

Results: Among the 876 subjects, 53% had normal glucose tolerance (NGT), and 47% had IGM. The ESC for the hands and feet was 72 +/- 10 mu S and 75 +/- 7 mu S, respectively, in NGT group; and 64 +/- 13 mu S and 67 +/- 11 mu S, respectively, in IGM group. The ESC at hands and feet was significantly correlated with both 2h-OGTT and FPG (p < 0.001). NGT group demonstrated a EZSCAN score of 33 +/- 11%, which is significantly lower than that of IGM group (44 +/- 12%, p < 0.001). The cut-off point of EZSCAN for IGM detection was 40% with a sensitivity of 80% and a specificity of 72%.

Conclusions: EZSCAN is a useful screening tool for identifying subjects at increased risk for impaired glucose metabolism in prediabetes and diabetes. Diagnostic laboratory test should be performed in subjects with EZSCAN scores greater than 40%. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

语种英语
WOS记录号WOS:000320590900017
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63794
专题北京大学第二临床医学院_心血管内科
作者单位1.Chongqing Med Univ, Dept Cardiol, Affiliated Hosp 1, Chongqing 400016, Peoples R China
2.Chongqing Med Univ, Chongqing 400016, Peoples R China
3.Peking Univ, Dept Cardiol, Peoples Hosp, Beijing 100044, Peoples R China
4.Xianghe Chinese Med Hosp, Dept Internal Med, Xianghe 065400, Hebei Province, Peoples R China
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GB/T 7714
Chen, Lizhu,Chen, Xiaolu,Ding, Rongjing,et al. Evaluation of EZSCAN as a screening tool for impaired glucose metabolism[J]. DIABETES RESEARCH AND CLINICAL PRACTICE,2013,100(2):210-214.
APA Chen, Lizhu,Chen, Xiaolu,Ding, Rongjing,Shi, Qiuting, Jr.,&Hu, Dayi.(2013).Evaluation of EZSCAN as a screening tool for impaired glucose metabolism.DIABETES RESEARCH AND CLINICAL PRACTICE,100(2),210-214.
MLA Chen, Lizhu,et al."Evaluation of EZSCAN as a screening tool for impaired glucose metabolism".DIABETES RESEARCH AND CLINICAL PRACTICE 100.2(2013):210-214.
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