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学科主题: 药学
题名:
A mini review of nanosuspensions development
作者: Liu, Yue; Xie, Pengcheng2; Zhang, Dianrui1; Zhang, Qiang3
关键词: Nanosuspensions ; discrimination ; production techniques ; stable measures ; special features ; routes of administration
刊名: JOURNAL OF DRUG TARGETING
发表日期: 2012-04-01
DOI: 10.3109/1061186X.2011.645161
卷: 20, 期:3, 页:209-223
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Pharmacology & Pharmacy
研究领域[WOS]: Pharmacology & Pharmacy
关键词[WOS]: POORLY SOLUBLE DRUGS ; GRAVITY REACTIVE PRECIPITATION ; TISSUE DISTRIBUTION ; ORAL BIOAVAILABILITY ; DELIVERY-SYSTEM ; MUCOADHESIVE NANOSUSPENSIONS ; FORMULATION DEVELOPMENT ; ANTITUMOR-ACTIVITY ; AMPHOTERICIN-B ; SIZE-REDUCTION
英文摘要:

Nanosuspension drug delivery has obtained great success in the preparation of insoluble drugs. The nanosuspension technology can confer a series of special characteristics to the drugs, such as the enhanced dissolution rate and saturation solubility. This mini review first described the differences between the nanocrystals and nanosuspensions. Next, the product techniques, the stable measures, the special features, and the routes of administration of the nanosuspensions were reviewed and compared. Finally, some existing shortcomings of the nanosuspensions were mentioned and the perspectives of the nanosuspensions were also made.

语种: 英语
所属项目编号: 2009CB930300
项目资助者: National Basic Research Program of China (973Program)
WOS记录号: WOS:000300878500002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63798
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Shandong Univ, Sch Pharm, Dept Pharmaceut, Coll Pharm, Jinan 250100, Shandong, Peoples R China
2.Jinan Petrochem Engn Design Inst, Jinan, Peoples R China
3.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100871, Peoples R China

Recommended Citation:
Liu, Yue,Xie, Pengcheng,Zhang, Dianrui,et al. A mini review of nanosuspensions development[J]. JOURNAL OF DRUG TARGETING,2012,20(3):209-223.
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