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A mini review of nanosuspensions development
Liu, Yue; Xie, Pengcheng2; Zhang, Dianrui1; Zhang, Qiang3
关键词Nanosuspensions discrimination production techniques stable measures special features routes of administration
刊名JOURNAL OF DRUG TARGETING
2012-04-01
DOI10.3109/1061186X.2011.645161
20期:3页:209-223
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]POORLY SOLUBLE DRUGS ; GRAVITY REACTIVE PRECIPITATION ; TISSUE DISTRIBUTION ; ORAL BIOAVAILABILITY ; DELIVERY-SYSTEM ; MUCOADHESIVE NANOSUSPENSIONS ; FORMULATION DEVELOPMENT ; ANTITUMOR-ACTIVITY ; AMPHOTERICIN-B ; SIZE-REDUCTION
英文摘要

Nanosuspension drug delivery has obtained great success in the preparation of insoluble drugs. The nanosuspension technology can confer a series of special characteristics to the drugs, such as the enhanced dissolution rate and saturation solubility. This mini review first described the differences between the nanocrystals and nanosuspensions. Next, the product techniques, the stable measures, the special features, and the routes of administration of the nanosuspensions were reviewed and compared. Finally, some existing shortcomings of the nanosuspensions were mentioned and the perspectives of the nanosuspensions were also made.

语种英语
WOS记录号WOS:000300878500002
项目编号2009CB930300
资助机构National Basic Research Program of China (973Program)
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被引频次:20[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63798
专题北京大学药学院
北京大学药学院_药剂学系
作者单位1.Shandong Univ, Sch Pharm, Dept Pharmaceut, Coll Pharm, Jinan 250100, Shandong, Peoples R China
2.Jinan Petrochem Engn Design Inst, Jinan, Peoples R China
3.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100871, Peoples R China
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GB/T 7714
Liu, Yue,Xie, Pengcheng,Zhang, Dianrui,et al. A mini review of nanosuspensions development[J]. JOURNAL OF DRUG TARGETING,2012,20(3):209-223.
APA Liu, Yue,Xie, Pengcheng,Zhang, Dianrui,&Zhang, Qiang.(2012).A mini review of nanosuspensions development.JOURNAL OF DRUG TARGETING,20(3),209-223.
MLA Liu, Yue,et al."A mini review of nanosuspensions development".JOURNAL OF DRUG TARGETING 20.3(2012):209-223.
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