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学科主题: 医学信息学
题名:
miREnvironment Database: providing a bridge for microRNAs, environmental factors and phenotypes
作者: Yang, Qingqing1,2; Qiu, Chengxiang1; Yang, Jie1,2; Wu, Qing2; Cui, Qinghua1,3,4
刊名: BIOINFORMATICS
发表日期: 2011-12-01
DOI: 10.1093/bioinformatics/btr556
卷: 27, 期:23, 页:3329-3330
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemical Research Methods ; Biotechnology & Applied Microbiology ; Computer Science, Interdisciplinary Applications ; Mathematical & Computational Biology ; Statistics & Probability
研究领域[WOS]: Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Computer Science ; Mathematical & Computational Biology ; Mathematics
关键词[WOS]: CANCER ; EXPRESSION ; PATHOGENESIS ; DISEASE ; LIVER
英文摘要:

The interaction between genetic factors and environmental factors has critical roles in determining the phenotype of an organism. In recent years, a number of studies have reported that the dysfunctions on microRNA (miRNAs), environmental factors and their interactions have strong effects on phenotypes and even may result in abnormal phenotypes and diseases, whereas there has been no a database linking miRNAs, environmental factors and phenotypes. Such a resource platform is believed to be of great value in the understanding of miRNAs, environmental factors, especially drugs and diseases. In this study, we constructed the miREnvironment database, which contains a comprehensive collection and curation of experimentally supported interactions among miRNAs, environmental factors and phenotypes. The names of miRNAs, phenotypes, environmental factors, conditions of environmental factors, samples, species, evidence and references were further annotated. miREnvironment represents a biomedical resource for researches on miRNAs, environmental factors and diseases.

语种: 英语
所属项目编号: 30900829
项目资助者: Natural Science Foundation of China
WOS记录号: WOS:000297352100021
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63801
Appears in Collections:基础医学院_医学信息学系_期刊论文

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作者单位: 1.Peking Univ, Inst Syst Biomed, Beijing 100191, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Dept Biomed Informat, Beijing 100191, Peoples R China
3.Hebei Univ Technol, Sch Comp Sci, Tianjin 300401, Peoples R China
4.Peking Univ, MOE Key Lab Mol Cardiovasc Sci, Beijing 100191, Peoples R China

Recommended Citation:
Yang, Qingqing,Qiu, Chengxiang,Yang, Jie,et al. miREnvironment Database: providing a bridge for microRNAs, environmental factors and phenotypes[J]. BIOINFORMATICS,2011,27(23):3329-3330.
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