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学科主题医学信息学
miREnvironment Database: providing a bridge for microRNAs, environmental factors and phenotypes
Yang, Qingqing1,2; Qiu, Chengxiang1; Yang, Jie1,2; Wu, Qing2; Cui, Qinghua1,3,4
刊名BIOINFORMATICS
2011-12-01
DOI10.1093/bioinformatics/btr556
27期:23页:3329-3330
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemical Research Methods ; Biotechnology & Applied Microbiology ; Computer Science, Interdisciplinary Applications ; Mathematical & Computational Biology ; Statistics & Probability
研究领域[WOS]Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Computer Science ; Mathematical & Computational Biology ; Mathematics
关键词[WOS]CANCER ; EXPRESSION ; PATHOGENESIS ; DISEASE ; LIVER
英文摘要

The interaction between genetic factors and environmental factors has critical roles in determining the phenotype of an organism. In recent years, a number of studies have reported that the dysfunctions on microRNA (miRNAs), environmental factors and their interactions have strong effects on phenotypes and even may result in abnormal phenotypes and diseases, whereas there has been no a database linking miRNAs, environmental factors and phenotypes. Such a resource platform is believed to be of great value in the understanding of miRNAs, environmental factors, especially drugs and diseases. In this study, we constructed the miREnvironment database, which contains a comprehensive collection and curation of experimentally supported interactions among miRNAs, environmental factors and phenotypes. The names of miRNAs, phenotypes, environmental factors, conditions of environmental factors, samples, species, evidence and references were further annotated. miREnvironment represents a biomedical resource for researches on miRNAs, environmental factors and diseases.

语种英语
WOS记录号WOS:000297352100021
项目编号30900829
资助机构Natural Science Foundation of China
引用统计
被引频次:41[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63801
专题北京大学基础医学院_医学信息学系
北京大学基础医学院
作者单位1.Peking Univ, Inst Syst Biomed, Beijing 100191, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Dept Biomed Informat, Beijing 100191, Peoples R China
3.Hebei Univ Technol, Sch Comp Sci, Tianjin 300401, Peoples R China
4.Peking Univ, MOE Key Lab Mol Cardiovasc Sci, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Yang, Qingqing,Qiu, Chengxiang,Yang, Jie,et al. miREnvironment Database: providing a bridge for microRNAs, environmental factors and phenotypes[J]. BIOINFORMATICS,2011,27(23):3329-3330.
APA Yang, Qingqing,Qiu, Chengxiang,Yang, Jie,Wu, Qing,&Cui, Qinghua.(2011).miREnvironment Database: providing a bridge for microRNAs, environmental factors and phenotypes.BIOINFORMATICS,27(23),3329-3330.
MLA Yang, Qingqing,et al."miREnvironment Database: providing a bridge for microRNAs, environmental factors and phenotypes".BIOINFORMATICS 27.23(2011):3329-3330.
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